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N-acetylcysteine reduces disease activity by blocking mammalian target of rapamycin in T cells from systemic lupus erythematosus patients: a randomized, double-blind, placebo-controlled trial.
Lai ZW, Hanczko R, Bonilla E, Caza TN, Clair B, Bartos A, Miklossy G, Jimah J, Doherty E, Tily H, Francis L, Garcia R, Dawood M, Yu J, Ramos I, Coman I, Faraone SV, Phillips PE, Perl A. Lai ZW, et al. Among authors: doherty e. Arthritis Rheum. 2012 Sep;64(9):2937-46. doi: 10.1002/art.34502. Arthritis Rheum. 2012. PMID: 22549432 Free PMC article. Clinical Trial.
T-cell and B-cell signaling biomarkers and treatment targets in lupus.
Perl A, Fernandez DR, Telarico T, Doherty E, Francis L, Phillips PE. Perl A, et al. Among authors: doherty e. Curr Opin Rheumatol. 2009 Sep;21(5):454-64. doi: 10.1097/BOR.0b013e32832e977c. Curr Opin Rheumatol. 2009. PMID: 19550330 Free PMC article. Review.
Prevention of hepatocarcinogenesis and increased susceptibility to acetaminophen-induced liver failure in transaldolase-deficient mice by N-acetylcysteine.
Hanczko R, Fernandez DR, Doherty E, Qian Y, Vas G, Niland B, Telarico T, Garba A, Banerjee S, Middleton FA, Barrett D, Barcza M, Banki K, Landas SK, Perl A. Hanczko R, et al. Among authors: doherty e. J Clin Invest. 2009 Jun;119(6):1546-57. doi: 10.1172/JCI35722. Epub 2009 May 11. J Clin Invest. 2009. PMID: 19436114 Free PMC article.
RNA language models predict mutations that improve RNA function.
Shulgina Y, Trinidad MI, Langeberg CJ, Nisonoff H, Chithrananda S, Skopintsev P, Nissley AJ, Patel J, Boger RS, Shi H, Yoon PH, Doherty EE, Pande T, Iyer AM, Doudna JA, Cate JHD. Shulgina Y, et al. Among authors: doherty ee. Nat Commun. 2024 Dec 5;15(1):10627. doi: 10.1038/s41467-024-54812-y. Nat Commun. 2024. PMID: 39638800 Free PMC article.
CD74 promotes the formation of an immunosuppressive tumor microenvironment in triple-negative breast cancer in mice by inducing the expansion of tolerogenic dendritic cells and regulatory B cells.
Pellegrino B, David K, Rabani S, Lampert B, Tran T, Doherty E, Piecychna M, Meza-Romero R, Leng L, Hershkovitz D, Vandenbark AA, Bucala R, Becker-Herman S, Shachar I. Pellegrino B, et al. Among authors: doherty e. PLoS Biol. 2024 Nov 22;22(11):e3002905. doi: 10.1371/journal.pbio.3002905. eCollection 2024 Nov. PLoS Biol. 2024. PMID: 39576827 Free PMC article.
398 results