Wynn TA - Search Results

1

Investigation of the binding pocket of human hematopoietic prostaglandin (PG) D2 synthase (hH-PGDS): a tale of two waters.

Trujillo JI, Kiefer JR, Huang W, Day JE, Moon J, Jerome GM, Bono CP, Kornmeier CM, Williams ML, Kuhn C, Rennie GR, Wynn TA, Carron CP, Thorarensen A. Trujillo JI, et al. Among authors: wynn ta. Bioorg Med Chem Lett. 2012 Jun 1;22(11):3795-9. doi: 10.1016/j.bmcl.2012.04.004. Epub 2012 Apr 13. Bioorg Med Chem Lett. 2012. PMID: 22546671

2

Structure of the catalytic domain of human polo-like kinase 1.

Kothe M, Kohls D, Low S, Coli R, Cheng AC, Jacques SL, Johnson TL, Lewis C, Loh C, Nonomiya J, Sheils AL, Verdries KA, Wynn TA, Kuhn C, Ding YH. Kothe M, et al. Among authors: wynn ta. Biochemistry. 2007 May 22;46(20):5960-71. doi: 10.1021/bi602474j. Epub 2007 Apr 27. Biochemistry. 2007. PMID: 17461553

3

Schistosoma mansoni arginase shares functional similarities with human orthologs but depends upon disulphide bridges for enzymatic activity.

Fitzpatrick JM, Fuentes JM, Chalmers IW, Wynn TA, Modolell M, Hoffmann KF, Hesse M. Fitzpatrick JM, et al. Among authors: wynn ta. Int J Parasitol. 2009 Feb;39(3):267-79. doi: 10.1016/j.ijpara.2008.06.015. Epub 2008 Aug 6. Int J Parasitol. 2009. PMID: 18723022 Free PMC article.

4

Macrophages as IL-25/IL-33-responsive cells play an important role in the induction of type 2 immunity.

Yang Z, Grinchuk V, Urban JF Jr, Bohl J, Sun R, Notari L, Yan S, Ramalingam T, Keegan AD, Wynn TA, Shea-Donohue T, Zhao A. Yang Z, et al. Among authors: wynn ta. PLoS One. 2013;8(3):e59441. doi: 10.1371/journal.pone.0059441. Epub 2013 Mar 25. PLoS One. 2013. PMID: 23536877 Free PMC article.

5

Cytokine-mediated host responses during schistosome infections; walking the fine line between immunological control and immunopathology.

Hoffmann KF, Wynn TA, Dunne DW. Hoffmann KF, et al. Among authors: wynn ta. Adv Parasitol. 2002;52:265-307. doi: 10.1016/s0065-308x(02)52014-5. Adv Parasitol. 2002. PMID: 12521263 Review.

6

Defining a schistosomiasis vaccination strategy - is it really Th1 versus Th2?

Wynn TA, Hoffmann KF. Wynn TA, et al. Parasitol Today. 2000 Nov;16(11):497-501. doi: 10.1016/s0169-4758(00)01788-9. Parasitol Today. 2000. PMID: 11063861 Review.

7

The guanine protein coupled receptor rhodopsin is developmentally regulated in the free-living stages of Schistosoma mansoni.

Hoffmann KF, Davis EM, Fischer ER, Wynn TA. Hoffmann KF, et al. Among authors: wynn ta. Mol Biochem Parasitol. 2001 Jan 15;112(1):113-23. doi: 10.1016/s0166-6851(00)00352-2. Mol Biochem Parasitol. 2001. PMID: 11166392

8

Differential regulation of nitric oxide synthase-2 and arginase-1 by type 1/type 2 cytokines in vivo: granulomatous pathology is shaped by the pattern of L-arginine metabolism.

Hesse M, Modolell M, La Flamme AC, Schito M, Fuentes JM, Cheever AW, Pearce EJ, Wynn TA. Hesse M, et al. Among authors: wynn ta. J Immunol. 2001 Dec 1;167(11):6533-44. doi: 10.4049/jimmunol.167.11.6533. J Immunol. 2001. PMID: 11714822

9

Studies with double cytokine-deficient mice reveal that highly polarized Th1- and Th2-type cytokine and antibody responses contribute equally to vaccine-induced immunity to Schistosoma mansoni.

Hoffmann KF, James SL, Cheever AW, Wynn TA. Hoffmann KF, et al. Among authors: wynn ta. J Immunol. 1999 Jul 15;163(2):927-38. J Immunol. 1999. PMID: 10395689

10

Immunopathology of schistosomiasis mansoni in mice and men.

Cheever AW, Hoffmann KF, Wynn TA. Cheever AW, et al. Among authors: wynn ta. Immunol Today. 2000 Sep;21(9):465-6. doi: 10.1016/s0167-5699(00)01626-1. Immunol Today. 2000. PMID: 10953099 No abstract available.

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