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Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism.
Ying H, Kimmelman AC, Lyssiotis CA, Hua S, Chu GC, Fletcher-Sananikone E, Locasale JW, Son J, Zhang H, Coloff JL, Yan H, Wang W, Chen S, Viale A, Zheng H, Paik JH, Lim C, Guimaraes AR, Martin ES, Chang J, Hezel AF, Perry SR, Hu J, Gan B, Xiao Y, Asara JM, Weissleder R, Wang YA, Chin L, Cantley LC, DePinho RA. Ying H, et al. Among authors: kimmelman ac. Cell. 2012 Apr 27;149(3):656-70. doi: 10.1016/j.cell.2012.01.058. Cell. 2012. PMID: 22541435 Free PMC article.
Reprogramming of tissue metabolism during cancer metastasis.
Ganguly K, Kimmelman AC. Ganguly K, et al. Among authors: kimmelman ac. Trends Cancer. 2023 Jun;9(6):461-471. doi: 10.1016/j.trecan.2023.02.005. Epub 2023 Mar 17. Trends Cancer. 2023. PMID: 36935322 Free PMC article. Review.
Genetics and biology of pancreatic ductal adenocarcinoma.
Hezel AF, Kimmelman AC, Stanger BZ, Bardeesy N, Depinho RA. Hezel AF, et al. Among authors: kimmelman ac. Genes Dev. 2006 May 15;20(10):1218-49. doi: 10.1101/gad.1415606. Genes Dev. 2006. PMID: 16702400 Free article. Review.
Stromal biology of pancreatic cancer.
Chu GC, Kimmelman AC, Hezel AF, DePinho RA. Chu GC, et al. Among authors: kimmelman ac. J Cell Biochem. 2007 Jul 1;101(4):887-907. doi: 10.1002/jcb.21209. J Cell Biochem. 2007. PMID: 17266048 Review.
p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation.
Zheng H, Ying H, Yan H, Kimmelman AC, Hiller DJ, Chen AJ, Perry SR, Tonon G, Chu GC, Ding Z, Stommel JM, Dunn KL, Wiedemeyer R, You MJ, Brennan C, Wang YA, Ligon KL, Wong WH, Chin L, DePinho RA. Zheng H, et al. Among authors: kimmelman ac. Nature. 2008 Oct 23;455(7216):1129-33. doi: 10.1038/nature07443. Nature. 2008. PMID: 18948956 Free PMC article.
Genomic alterations link Rho family of GTPases to the highly invasive phenotype of pancreas cancer.
Kimmelman AC, Hezel AF, Aguirre AJ, Zheng H, Paik JH, Ying H, Chu GC, Zhang JX, Sahin E, Yeo G, Ponugoti A, Nabioullin R, Deroo S, Yang S, Wang X, McGrath JP, Protopopova M, Ivanova E, Zhang J, Feng B, Tsao MS, Redston M, Protopopov A, Xiao Y, Futreal PA, Hahn WC, Klimstra DS, Chin L, DePinho RA. Kimmelman AC, et al. Proc Natl Acad Sci U S A. 2008 Dec 9;105(49):19372-7. doi: 10.1073/pnas.0809966105. Epub 2008 Dec 2. Proc Natl Acad Sci U S A. 2008. PMID: 19050074 Free PMC article.
Pten and p53 converge on c-Myc to control differentiation, self-renewal, and transformation of normal and neoplastic stem cells in glioblastoma.
Zheng H, Ying H, Yan H, Kimmelman AC, Hiller DJ, Chen AJ, Perry SR, Tonon G, Chu GC, Ding Z, Stommel JM, Dunn KL, Wiedemeyer R, You MJ, Brennan C, Wang YA, Ligon KL, Wong WH, Chin L, dePinho RA. Zheng H, et al. Among authors: kimmelman ac. Cold Spring Harb Symp Quant Biol. 2008;73:427-37. doi: 10.1101/sqb.2008.73.047. Epub 2009 Jan 15. Cold Spring Harb Symp Quant Biol. 2008. PMID: 19150964
119 results