van der Sloot AM - Search Results

1

A novel classification system to predict the pathogenic effects of CHD7 missense variants in CHARGE syndrome.

Bergman JE, Janssen N, van der Sloot AM, de Walle HE, Schoots J, Rendtorff ND, Tranebjaerg L, Hoefsloot LH, van Ravenswaaij-Arts CM, Hofstra RM. Bergman JE, et al. Among authors: van ravenswaaij arts cm, van der sloot am. Hum Mutat. 2012 Aug;33(8):1251-60. doi: 10.1002/humu.22106. Epub 2012 May 11. Hum Mutat. 2012. PMID: 22539353

2

RET-familial medullary thyroid carcinoma mutants Y791F and S891A activate a Src/JAK/STAT3 pathway, independent of glial cell line-derived neurotrophic factor.

Plaza Menacho I, Koster R, van der Sloot AM, Quax WJ, Osinga J, van der Sluis T, Hollema H, Burzynski GM, Gimm O, Buys CH, Eggen BJ, Hofstra RM. Plaza Menacho I, et al. Among authors: van der sluis t, van der sloot am. Cancer Res. 2005 Mar 1;65(5):1729-37. doi: 10.1158/0008-5472.CAN-04-2363. Cancer Res. 2005. PMID: 15753368

3

Evaluating CHARGE syndrome in congenital hypogonadotropic hypogonadism patients harboring CHD7 variants.

Xu C, Cassatella D, van der Sloot AM, Quinton R, Hauschild M, De Geyter C, Flück C, Feller K, Bartholdi D, Nemeth A, Halperin I, Pekic Djurdjevic S, Maeder P, Papadakis G, Dwyer AA, Marino L, Favre L, Pignatelli D, Niederländer NJ, Acierno J, Pitteloud N. Xu C, et al. Among authors: van der sloot am. Genet Med. 2018 Aug;20(8):872-881. doi: 10.1038/gim.2017.197. Epub 2017 Nov 16. Genet Med. 2018. PMID: 29144511 Free article.

4

Rapid and efficient cancer cell killing mediated by high-affinity death receptor homotrimerizing TRAIL variants.

Reis CR, van der Sloot AM, Natoni A, Szegezdi E, Setroikromo R, Meijer M, Sjollema K, Stricher F, Cool RH, Samali A, Serrano L, Quax WJ. Reis CR, et al. Among authors: van der sloot am. Cell Death Dis. 2010 Oct 21;1(10):e83. doi: 10.1038/cddis.2010.61. Cell Death Dis. 2010. PMID: 21368856 Free PMC article.

5

A novel genetic selection system for improved enantioselectivity of Bacillus subtilis lipase A.

Boersma YL, Dröge MJ, van der Sloot AM, Pijning T, Cool RH, Dijkstra BW, Quax WJ. Boersma YL, et al. Among authors: van der sloot am. Chembiochem. 2008 May 5;9(7):1110-5. doi: 10.1002/cbic.200700754. Chembiochem. 2008. PMID: 18383241

6

Loop grafting of Bacillus subtilis lipase A: inversion of enantioselectivity.

Boersma YL, Pijning T, Bosma MS, van der Sloot AM, Godinho LF, Dröge MJ, Winter RT, van Pouderoyen G, Dijkstra BW, Quax WJ. Boersma YL, et al. Among authors: van pouderoyen g, van der sloot am. Chem Biol. 2008 Aug 25;15(8):782-9. doi: 10.1016/j.chembiol.2008.06.009. Chem Biol. 2008. PMID: 18721749

7

Mutational analysis of a key residue in the substrate specificity of a cephalosporin acylase.

Otten LG, Sio CF, van der Sloot AM, Cool RH, Quax WJ. Otten LG, et al. Among authors: van der sloot am. Chembiochem. 2004 Jun 7;5(6):820-5. doi: 10.1002/cbic.200300764. Chembiochem. 2004. PMID: 15174165

8

Stabilization of TRAIL, an all-beta-sheet multimeric protein, using computational redesign.

van der Sloot AM, Mullally MM, Fernandez-Ballester G, Serrano L, Quax WJ. van der Sloot AM, et al. Protein Eng Des Sel. 2004 Sep;17(9):673-80. doi: 10.1093/protein/gzh079. Epub 2004 Oct 14. Protein Eng Des Sel. 2004. PMID: 15486023

9

Designed tumor necrosis factor-related apoptosis-inducing ligand variants initiating apoptosis exclusively via the DR5 receptor.

van der Sloot AM, Tur V, Szegezdi E, Mullally MM, Cool RH, Samali A, Serrano L, Quax WJ. van der Sloot AM, et al. Proc Natl Acad Sci U S A. 2006 Jun 6;103(23):8634-9. doi: 10.1073/pnas.0510187103. Epub 2006 May 26. Proc Natl Acad Sci U S A. 2006. PMID: 16731632 Free PMC article.

10

Enhancement of antitumor properties of rhTRAIL by affinity increase toward its death receptors.

Reis CR, van der Sloot AM, Szegezdi E, Natoni A, Tur V, Cool RH, Samali A, Serrano L, Quax WJ. Reis CR, et al. Among authors: van der sloot am. Biochemistry. 2009 Mar 17;48(10):2180-91. doi: 10.1021/bi801927x. Biochemistry. 2009. PMID: 19236007

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