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7-MEOTA-donepezil like compounds as cholinesterase inhibitors: Synthesis, pharmacological evaluation, molecular modeling and QSAR studies.
Korabecny J, Dolezal R, Cabelova P, Horova A, Hruba E, Ricny J, Sedlacek L, Nepovimova E, Spilovska K, Andrs M, Musilek K, Opletalova V, Sepsova V, Ripova D, Kuca K. Korabecny J, et al. Among authors: hruba e. Eur J Med Chem. 2014 Jul 23;82:426-38. doi: 10.1016/j.ejmech.2014.05.066. Epub 2014 May 27. Eur J Med Chem. 2014. PMID: 24929293
TGF-β1 signaling plays a dominant role in the crosstalk between TGF-β1 and the aryl hydrocarbon receptor ligand in prostate epithelial cells.
Staršíchová A, Hrubá E, Slabáková E, Pernicová Z, Procházková J, Pěnčíková K, Seda V, Kabátková M, Vondráček J, Kozubík A, Machala M, Souček K. Staršíchová A, et al. Among authors: hruba e. Cell Signal. 2012 Aug;24(8):1665-76. doi: 10.1016/j.cellsig.2012.04.008. Epub 2012 Apr 25. Cell Signal. 2012. PMID: 22560882
Atropisomers of 2,2',3,3',6,6'-hexachlorobiphenyl (PCB 136) exhibit stereoselective effects on activation of nuclear receptors in vitro.
Pěnčíková K, Brenerová P, Svržková L, Hrubá E, Pálková L, Vondráček J, Lehmler HJ, Machala M. Pěnčíková K, et al. Among authors: hruba e. Environ Sci Pollut Res Int. 2018 Jun;25(17):16411-16419. doi: 10.1007/s11356-017-0683-x. Epub 2017 Nov 9. Environ Sci Pollut Res Int. 2018. PMID: 29124635 Free PMC article.
Adaptive changes in global gene expression profile of lung carcinoma A549 cells acutely exposed to distinct types of AhR ligands.
Procházková J, Strapáčová S, Svržková L, Andrysík Z, Hýžďalová M, Hrubá E, Pěnčíková K, Líbalová H, Topinka J, Kléma J, Espinosa JM, Vondráček J, Machala M. Procházková J, et al. Among authors: hruba e. Toxicol Lett. 2018 Aug;292:162-174. doi: 10.1016/j.toxlet.2018.04.024. Epub 2018 Apr 25. Toxicol Lett. 2018. PMID: 29704546
A prolonged exposure of human lung carcinoma epithelial cells to benzo[a]pyrene induces p21-dependent epithelial-to-mesenchymal transition (EMT)-like phenotype.
Hýžďalová M, Procházková J, Strapáčová S, Svržková L, Vacek O, Fedr R, Andrysík Z, Hrubá E, Líbalová H, Kléma J, Topinka J, Mašek J, Souček K, Vondráček J, Machala M. Hýžďalová M, et al. Among authors: hruba e. Chemosphere. 2021 Jan;263:128126. doi: 10.1016/j.chemosphere.2020.128126. Epub 2020 Sep 10. Chemosphere. 2021. PMID: 33297115
AhR-mediated changes in global gene expression in rat liver progenitor cells.
Faust D, Vondráček J, Krčmář P, Smerdová L, Procházková J, Hrubá E, Hulinková P, Kaina B, Dietrich C, Machala M. Faust D, et al. Among authors: hruba e. Arch Toxicol. 2013 Apr;87(4):681-98. doi: 10.1007/s00204-012-0979-z. Epub 2012 Nov 30. Arch Toxicol. 2013. PMID: 23196670
34 results