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Agonist effects of zinterol at the mouse and human beta(3)-adrenoceptor.
Hutchinson DS, Chernogubova E, Sato M, Summers RJ, Bengtsson T. Hutchinson DS, et al. Among authors: sato m. Naunyn Schmiedebergs Arch Pharmacol. 2006 May;373(2):158-68. doi: 10.1007/s00210-006-0056-3. Epub 2006 Apr 7. Naunyn Schmiedebergs Arch Pharmacol. 2006. PMID: 16601951
The beta3-adrenoceptor agonist 4-[[(Hexylamino)carbonyl]amino]-N-[4-[2-[[(2S)-2-hydroxy-3-(4-hydroxyphenoxy)propyl]amino]ethyl]-phenyl]-benzenesulfonamide (L755507) and antagonist (S)-N-[4-[2-[[3-[3-(acetamidomethyl)phenoxy]-2-hydroxypropyl]amino]-ethyl]phenyl]benzenesulfonamide (L748337) activate different signaling pathways in Chinese hamster ovary-K1 cells stably expressing the human beta3-adrenoceptor.
Sato M, Hutchinson DS, Evans BA, Summers RJ. Sato M, et al. Mol Pharmacol. 2008 Nov;74(5):1417-28. doi: 10.1124/mol.108.046979. Epub 2008 Aug 6. Mol Pharmacol. 2008. PMID: 18684840
Ligand-directed signalling at beta-adrenoceptors.
Evans BA, Sato M, Sarwar M, Hutchinson DS, Summers RJ. Evans BA, et al. Among authors: sato m. Br J Pharmacol. 2010 Mar;159(5):1022-38. doi: 10.1111/j.1476-5381.2009.00602.x. Epub 2010 Feb 2. Br J Pharmacol. 2010. PMID: 20132209 Free PMC article. Review.
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