Donehower LA - Search Results

1

Mouse tissues that undergo neoplastic progression after K-Ras activation are distinguished by nuclear translocation of phospho-Erk1/2 and robust tumor suppressor responses.

Parikh N, Shuck RL, Nguyen TA, Herron A, Donehower LA. Parikh N, et al. Among authors: donehower la. Mol Cancer Res. 2012 Jun;10(6):845-55. doi: 10.1158/1541-7786.MCR-12-0089. Epub 2012 Apr 24. Mol Cancer Res. 2012. PMID: 22532587 Free PMC article.

2

Enhanced inflammation and attenuated tumor suppressor pathways are associated with oncogene-induced lung tumors in aged mice.

Parikh N, Shuck RL, Gagea M, Shen L, Donehower LA. Parikh N, et al. Among authors: donehower la. Aging Cell. 2018 Feb;17(1):e12691. doi: 10.1111/acel.12691. Epub 2017 Oct 18. Aging Cell. 2018. PMID: 29047229 Free PMC article.

3

Homeostatic regulation of base excision repair by a p53-induced phosphatase: linking stress response pathways with DNA repair proteins.

Lu X, Nguyen TA, Appella E, Donehower LA. Lu X, et al. Among authors: donehower la. Cell Cycle. 2004 Nov;3(11):1363-6. doi: 10.4161/cc.3.11.1241. Epub 2004 Nov 15. Cell Cycle. 2004. PMID: 15539943

4

Reversal of the ATM/ATR-mediated DNA damage response by the oncogenic phosphatase PPM1D.

Lu X, Nguyen TA, Donehower LA. Lu X, et al. Among authors: donehower la. Cell Cycle. 2005 Aug;4(8):1060-4. Epub 2005 Aug 26. Cell Cycle. 2005. PMID: 15970689

5

Augmented cancer resistance and DNA damage response phenotypes in PPM1D null mice.

Nannenga B, Lu X, Dumble M, Van Maanen M, Nguyen TA, Sutton R, Kumar TR, Donehower LA. Nannenga B, et al. Among authors: donehower la. Mol Carcinog. 2006 Aug;45(8):594-604. doi: 10.1002/mc.20195. Mol Carcinog. 2006. PMID: 16652371

6

The type 2C phosphatase Wip1: an oncogenic regulator of tumor suppressor and DNA damage response pathways.

Lu X, Nguyen TA, Moon SH, Darlington Y, Sommer M, Donehower LA. Lu X, et al. Among authors: donehower la. Cancer Metastasis Rev. 2008 Jun;27(2):123-35. doi: 10.1007/s10555-008-9127-x. Cancer Metastasis Rev. 2008. PMID: 18265945 Free PMC article. Review.

7

MMP13, Birc2 (cIAP1), and Birc3 (cIAP2), amplified on chromosome 9, collaborate with p53 deficiency in mouse osteosarcoma progression.

Ma O, Cai WW, Zender L, Dayaram T, Shen J, Herron AJ, Lowe SW, Man TK, Lau CC, Donehower LA. Ma O, et al. Among authors: donehower la. Cancer Res. 2009 Mar 15;69(6):2559-67. doi: 10.1158/0008-5472.CAN-08-2929. Epub 2009 Mar 10. Cancer Res. 2009. PMID: 19276372 Free PMC article.

8

Altered senescence, apoptosis, and DNA damage response in a mutant p53 model of accelerated aging.

Hinkal GW, Gatza CE, Parikh N, Donehower LA. Hinkal GW, et al. Among authors: donehower la. Mech Ageing Dev. 2009 Apr;130(4):262-71. doi: 10.1016/j.mad.2009.01.001. Mech Ageing Dev. 2009. PMID: 19396980 Free PMC article.

9

Timed somatic deletion of p53 in mice reveals age-associated differences in tumor progression.

Hinkal G, Parikh N, Donehower LA. Hinkal G, et al. Among authors: donehower la. PLoS One. 2009 Aug 14;4(8):e6654. doi: 10.1371/journal.pone.0006654. PLoS One. 2009. PMID: 19680549 Free PMC article.

10

Disrupting circadian homeostasis of sympathetic signaling promotes tumor development in mice.

Lee S, Donehower LA, Herron AJ, Moore DD, Fu L. Lee S, et al. Among authors: donehower la. PLoS One. 2010 Jun 7;5(6):e10995. doi: 10.1371/journal.pone.0010995. PLoS One. 2010. PMID: 20539819 Free PMC article.

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