Scruggs SB - Search Results

1

Protein kinase C depresses cardiac myocyte power output and attenuates myofilament responses induced by protein kinase A.

Hinken AC, Hanft LM, Scruggs SB, Sadayappan S, Robbins J, Solaro RJ, McDonald KS. Hinken AC, et al. Among authors: scruggs sb. J Muscle Res Cell Motil. 2012 Dec;33(6):439-48. doi: 10.1007/s10974-012-9294-9. Epub 2012 Apr 22. J Muscle Res Cell Motil. 2012. PMID: 22527640 Free PMC article.

2

Ablation of ventricular myosin regulatory light chain phosphorylation in mice causes cardiac dysfunction in situ and affects neighboring myofilament protein phosphorylation.

Scruggs SB, Hinken AC, Thawornkaiwong A, Robbins J, Walker LA, de Tombe PP, Geenen DL, Buttrick PM, Solaro RJ. Scruggs SB, et al. J Biol Chem. 2009 Feb 20;284(8):5097-106. doi: 10.1074/jbc.M807414200. Epub 2008 Dec 23. J Biol Chem. 2009. PMID: 19106098 Free PMC article.

3

Partial replacement of cardiac troponin I with a non-phosphorylatable mutant at serines 43/45 attenuates the contractile dysfunction associated with PKCepsilon phosphorylation.

Scruggs SB, Walker LA, Lyu T, Geenen DL, Solaro RJ, Buttrick PM, Goldspink PH. Scruggs SB, et al. J Mol Cell Cardiol. 2006 Apr;40(4):465-73. doi: 10.1016/j.yjmcc.2005.12.009. Epub 2006 Jan 30. J Mol Cell Cardiol. 2006. PMID: 16445938

4

The significance of regulatory light chain phosphorylation in cardiac physiology.

Scruggs SB, Solaro RJ. Scruggs SB, et al. Arch Biochem Biophys. 2011 Jun 15;510(2):129-34. doi: 10.1016/j.abb.2011.02.013. Epub 2011 Feb 21. Arch Biochem Biophys. 2011. PMID: 21345328 Free PMC article. Review.

5

New insights into the functional significance of the acidic region of the unique N-terminal extension of cardiac troponin I.

Henze M, Patrick SE, Hinken A, Scruggs SB, Goldspink P, de Tombe PP, Kobayashi M, Ping P, Kobayashi T, Solaro RJ. Henze M, et al. Among authors: scruggs sb. Biochim Biophys Acta. 2013 Apr;1833(4):823-32. doi: 10.1016/j.bbamcr.2012.08.012. Epub 2012 Aug 25. Biochim Biophys Acta. 2013. PMID: 22940544 Free PMC article.

6

A novel, in-solution separation of endogenous cardiac sarcomeric proteins and identification of distinct charged variants of regulatory light chain.

Scruggs SB, Reisdorph R, Armstrong ML, Warren CM, Reisdorph N, Solaro RJ, Buttrick PM. Scruggs SB, et al. Mol Cell Proteomics. 2010 Sep;9(9):1804-18. doi: 10.1074/mcp.M110.000075. Epub 2010 May 5. Mol Cell Proteomics. 2010. PMID: 20445002 Free PMC article.

7

Myocardial infarction in mice alters sarcomeric function via post-translational protein modification.

Avner BS, Shioura KM, Scruggs SB, Grachoff M, Geenen DL, Helseth DL Jr, Farjah M, Goldspink PH, Solaro RJ. Avner BS, et al. Among authors: scruggs sb. Mol Cell Biochem. 2012 Apr;363(1-2):203-15. doi: 10.1007/s11010-011-1172-z. Epub 2011 Dec 8. Mol Cell Biochem. 2012. PMID: 22160857 Free PMC article.

8

Why is it important to analyze the cardiac sarcomere subproteome?

Solaro RJ, Warren CM, Scruggs SB. Solaro RJ, et al. Among authors: scruggs sb. Expert Rev Proteomics. 2010 Jun;7(3):311-4. doi: 10.1586/epr.10.15. Expert Rev Proteomics. 2010. PMID: 20536300 Free PMC article. No abstract available.

9

Post-translational modification of cardiac proteasomes: functional delineation enabled by proteomics.

Scruggs SB, Zong NC, Wang D, Stefani E, Ping P. Scruggs SB, et al. Am J Physiol Heart Circ Physiol. 2012 Jul;303(1):H9-18. doi: 10.1152/ajpheart.00189.2012. Epub 2012 Apr 20. Am J Physiol Heart Circ Physiol. 2012. PMID: 22523251 Free PMC article. Review.

10

PRKCE gene encoding protein kinase C-epsilon-Dual roles at sarcomeres and mitochondria in cardiomyocytes.

Scruggs SB, Wang D, Ping P. Scruggs SB, et al. Gene. 2016 Sep 15;590(1):90-6. doi: 10.1016/j.gene.2016.06.016. Epub 2016 Jun 13. Gene. 2016. PMID: 27312950 Free PMC article. Review.

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