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Toward computational identification of multiscale "tipping points" in acute inflammation and multiple organ failure.
An G, Nieman G, Vodovotz Y. An G, et al. Ann Biomed Eng. 2012 Nov;40(11):2414-24. doi: 10.1007/s10439-012-0565-9. Epub 2012 Apr 21. Ann Biomed Eng. 2012. PMID: 22527009
Properly regulated inflammation allows for timely recognition and effective reaction to injury or infection, but inadequate or overly robust inflammation can lead to Multiple Organ Dysfunction Syndrome (MODS). There is an incongruity between the systemic nature of disorder …
Properly regulated inflammation allows for timely recognition and effective reaction to injury or infection, but inadequate or overly robust …
Mathematical models of the acute inflammatory response.
Vodovotz Y, Clermont G, Chow C, An G. Vodovotz Y, et al. Among authors: an g. Curr Opin Crit Care. 2004 Oct;10(5):383-90. doi: 10.1097/01.ccx.0000139360.30327.69. Curr Opin Crit Care. 2004. PMID: 15385756 Review.
Translational systems biology of inflammation.
Vodovotz Y, Csete M, Bartels J, Chang S, An G. Vodovotz Y, et al. Among authors: an g. PLoS Comput Biol. 2008 Apr 25;4(4):e1000014. doi: 10.1371/journal.pcbi.1000014. PLoS Comput Biol. 2008. PMID: 18437239 Free PMC article. Review.
Translational systems biology and voice pathophysiology.
Li NY, Abbott KV, Rosen C, An G, Hebda PA, Vodovotz Y. Li NY, et al. Among authors: an g. Laryngoscope. 2010 Mar;120(3):511-5. doi: 10.1002/lary.20755. Laryngoscope. 2010. PMID: 20025041 Free PMC article. Review.
Translational systems approaches to the biology of inflammation and healing.
Vodovotz Y, Constantine G, Faeder J, Mi Q, Rubin J, Bartels J, Sarkar J, Squires RH Jr, Okonkwo DO, Gerlach J, Zamora R, Luckhart S, Ermentrout B, An G. Vodovotz Y, et al. Among authors: an g. Immunopharmacol Immunotoxicol. 2010 Jun;32(2):181-95. doi: 10.3109/08923970903369867. Immunopharmacol Immunotoxicol. 2010. PMID: 20170421 Free PMC article. Review.
A systems-based understanding of inflammation, coupled to translational applications, is therefore necessary for efficient development of drugs and devices, for streamlining analyses at the level of populations, and for the implementation of personalized medicine. We have carried …
A systems-based understanding of inflammation, coupled to translational applications, is therefore necessary for efficient development of dr …
Systems biology and inflammation.
Vodovotz Y, An G. Vodovotz Y, et al. Among authors: an g. Methods Mol Biol. 2010;662:181-201. doi: 10.1007/978-1-60761-800-3_9. Methods Mol Biol. 2010. PMID: 20824472
1,745 results