Bowton E - Search Results

1

Attention deficit/hyperactivity disorder-derived coding variation in the dopamine transporter disrupts microdomain targeting and trafficking regulation.

Sakrikar D, Mazei-Robison MS, Mergy MA, Richtand NW, Han Q, Hamilton PJ, Bowton E, Galli A, Veenstra-Vanderweele J, Gill M, Blakely RD. Sakrikar D, et al. Among authors: bowton e. J Neurosci. 2012 Apr 18;32(16):5385-97. doi: 10.1523/JNEUROSCI.6033-11.2012. J Neurosci. 2012. PMID: 22514303 Free PMC article.

2

SLC6A3 coding variant Ala559Val found in two autism probands alters dopamine transporter function and trafficking.

Bowton E, Saunders C, Reddy IA, Campbell NG, Hamilton PJ, Henry LK, Coon H, Sakrikar D, Veenstra-VanderWeele JM, Blakely RD, Sutcliffe J, Matthies HJ, Erreger K, Galli A. Bowton E, et al. Transl Psychiatry. 2014 Oct 14;4(10):e464. doi: 10.1038/tp.2014.90. Transl Psychiatry. 2014. PMID: 25313507 Free PMC article.

3

Anomalous dopamine release associated with a human dopamine transporter coding variant.

Mazei-Robison MS, Bowton E, Holy M, Schmudermaier M, Freissmuth M, Sitte HH, Galli A, Blakely RD. Mazei-Robison MS, et al. Among authors: bowton e. J Neurosci. 2008 Jul 9;28(28):7040-6. doi: 10.1523/JNEUROSCI.0473-08.2008. J Neurosci. 2008. PMID: 18614672 Free PMC article.

4

Dysregulation of dopamine transporters via dopamine D2 autoreceptors triggers anomalous dopamine efflux associated with attention-deficit hyperactivity disorder.

Bowton E, Saunders C, Erreger K, Sakrikar D, Matthies HJ, Sen N, Jessen T, Colbran RJ, Caron MG, Javitch JA, Blakely RD, Galli A. Bowton E, et al. J Neurosci. 2010 Apr 28;30(17):6048-57. doi: 10.1523/JNEUROSCI.5094-09.2010. J Neurosci. 2010. PMID: 20427663 Free PMC article.

5

Syntaxin 1A interaction with the dopamine transporter promotes amphetamine-induced dopamine efflux.

Binda F, Dipace C, Bowton E, Robertson SD, Lute BJ, Fog JU, Zhang M, Sen N, Colbran RJ, Gnegy ME, Gether U, Javitch JA, Erreger K, Galli A. Binda F, et al. Among authors: bowton e. Mol Pharmacol. 2008 Oct;74(4):1101-8. doi: 10.1124/mol.108.048447. Epub 2008 Jul 10. Mol Pharmacol. 2008. PMID: 18617632 Free PMC article.

6

Calmodulin kinase II interacts with the dopamine transporter C terminus to regulate amphetamine-induced reverse transport.

Fog JU, Khoshbouei H, Holy M, Owens WA, Vaegter CB, Sen N, Nikandrova Y, Bowton E, McMahon DG, Colbran RJ, Daws LC, Sitte HH, Javitch JA, Galli A, Gether U. Fog JU, et al. Among authors: bowton e. Neuron. 2006 Aug 17;51(4):417-29. doi: 10.1016/j.neuron.2006.06.028. Neuron. 2006. PMID: 16908408 Free article.

7

A juxtamembrane mutation in the N terminus of the dopamine transporter induces preference for an inward-facing conformation.

Guptaroy B, Zhang M, Bowton E, Binda F, Shi L, Weinstein H, Galli A, Javitch JA, Neubig RR, Gnegy ME. Guptaroy B, et al. Among authors: bowton e. Mol Pharmacol. 2009 Mar;75(3):514-24. doi: 10.1124/mol.108.048744. Epub 2008 Dec 19. Mol Pharmacol. 2009. PMID: 19098122 Free PMC article.

8

Flotillin-1 is essential for PKC-triggered endocytosis and membrane microdomain localization of DAT.

Cremona ML, Matthies HJ, Pau K, Bowton E, Speed N, Lute BJ, Anderson M, Sen N, Robertson SD, Vaughan RA, Rothman JE, Galli A, Javitch JA, Yamamoto A. Cremona ML, et al. Among authors: bowton e. Nat Neurosci. 2011 Apr;14(4):469-77. doi: 10.1038/nn.2781. Epub 2011 Mar 13. Nat Neurosci. 2011. PMID: 21399631 Free PMC article.

9

Predicting warfarin dosage in European-Americans and African-Americans using DNA samples linked to an electronic health record.

Ramirez AH, Shi Y, Schildcrout JS, Delaney JT, Xu H, Oetjens MT, Zuvich RL, Basford MA, Bowton E, Jiang M, Speltz P, Zink R, Cowan J, Pulley JM, Ritchie MD, Masys DR, Roden DM, Crawford DC, Denny JC. Ramirez AH, et al. Among authors: bowton e. Pharmacogenomics. 2012 Mar;13(4):407-18. doi: 10.2217/pgs.11.164. Epub 2012 Feb 13. Pharmacogenomics. 2012. PMID: 22329724 Free PMC article.

10

Optimizing drug outcomes through pharmacogenetics: a case for preemptive genotyping.

Schildcrout JS, Denny JC, Bowton E, Gregg W, Pulley JM, Basford MA, Cowan JD, Xu H, Ramirez AH, Crawford DC, Ritchie MD, Peterson JF, Masys DR, Wilke RA, Roden DM. Schildcrout JS, et al. Among authors: bowton e. Clin Pharmacol Ther. 2012 Aug;92(2):235-42. doi: 10.1038/clpt.2012.66. Epub 2012 Jun 27. Clin Pharmacol Ther. 2012. PMID: 22739144 Free PMC article.

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