Harris JM - Search Results

1

Non-combinatorial library screening reveals subsite cooperativity and identifies new high-efficiency substrates for kallikrein-related peptidase 14.

de Veer SJ, Swedberg JE, Parker EA, Harris JM. de Veer SJ, et al. Among authors: harris jm. Biol Chem. 2012 Apr;393(5):331-41. doi: 10.1515/bc-2011-250. Biol Chem. 2012. PMID: 22505516 Free article.

2

Selective cleavage of human sex hormone-binding globulin by kallikrein-related peptidases and effects on androgen action in LNCaP prostate cancer cells.

Sanchez WY, de Veer SJ, Swedberg JE, Hong EJ, Reid JC, Walsh TP, Hooper JD, Hammond GL, Clements JA, Harris JM. Sanchez WY, et al. Among authors: harris jm. Endocrinology. 2012 Jul;153(7):3179-89. doi: 10.1210/en.2012-1011. Epub 2012 Apr 30. Endocrinology. 2012. PMID: 22547569 Free article.

3

Mechanism-based selection of a potent kallikrein-related peptidase 7 inhibitor from a versatile library based on the sunflower trypsin inhibitor SFTI-1.

de Veer SJ, Ukolova SS, Munro CA, Swedberg JE, Buckle AM, Harris JM. de Veer SJ, et al. Among authors: harris jm. Biopolymers. 2013 Mar 11. doi: 10.1002/peps.22231. Online ahead of print. Biopolymers. 2013. PMID: 23494567

4

Mechanism-based selection of a potent kallikrein-related peptidase 7 inhibitor from a versatile library based on the sunflower trypsin inhibitor SFTI-1.

de Veer SJ, Ukolova SS, Munro CA, Swedberg JE, Buckle AM, Harris JM. de Veer SJ, et al. Among authors: harris jm. Biopolymers. 2013 Sep;100(5):510-8. doi: 10.1002/bip.22231. Biopolymers. 2013. PMID: 24078181

5

Engineered protease inhibitors based on sunflower trypsin inhibitor-1 (SFTI-1) provide insights into the role of sequence and conformation in Laskowski mechanism inhibition.

de Veer SJ, Swedberg JE, Akcan M, Rosengren KJ, Brattsand M, Craik DJ, Harris JM. de Veer SJ, et al. Among authors: harris jm. Biochem J. 2015 Jul 15;469(2):243-53. doi: 10.1042/BJ20150412. Epub 2015 May 18. Biochem J. 2015. PMID: 25981970

6

Improving the Selectivity of Engineered Protease Inhibitors: Optimizing the P2 Prime Residue Using a Versatile Cyclic Peptide Library.

de Veer SJ, Wang CK, Harris JM, Craik DJ, Swedberg JE. de Veer SJ, et al. Among authors: harris jm. J Med Chem. 2015 Oct 22;58(20):8257-68. doi: 10.1021/acs.jmedchem.5b01148. Epub 2015 Oct 5. J Med Chem. 2015. PMID: 26393374

7

Exploring the active site binding specificity of kallikrein-related peptidase 5 (KLK5) guides the design of new peptide substrates and inhibitors.

de Veer SJ, Swedberg JE, Brattsand M, Clements JA, Harris JM. de Veer SJ, et al. Among authors: harris jm. Biol Chem. 2016 Dec 1;397(12):1237-1249. doi: 10.1515/hsz-2016-0112. Biol Chem. 2016. PMID: 26894578

8

Selective Substrates and Inhibitors for Kallikrein-Related Peptidase 7 (KLK7) Shed Light on KLK Proteolytic Activity in the Stratum Corneum.

de Veer SJ, Furio L, Swedberg JE, Munro CA, Brattsand M, Clements JA, Hovnanian A, Harris JM. de Veer SJ, et al. Among authors: harris jm. J Invest Dermatol. 2017 Feb;137(2):430-439. doi: 10.1016/j.jid.2016.09.017. Epub 2016 Sep 30. J Invest Dermatol. 2017. PMID: 27697464 Free article.

9

Direct and indirect mechanisms of KLK4 inhibition revealed by structure and dynamics.

Riley BT, Ilyichova O, Costa MG, Porebski BT, de Veer SJ, Swedberg JE, Kass I, Harris JM, Hoke DE, Buckle AM. Riley BT, et al. Among authors: harris jm. Sci Rep. 2016 Oct 21;6:35385. doi: 10.1038/srep35385. Sci Rep. 2016. PMID: 27767076 Free PMC article.

10

Potent, Selective, and Cell-Penetrating Inhibitors of Kallikrein-Related Peptidase 4 Based on the Cyclic Peptide MCoTI-II.

Swedberg JE, Ghani HA, Harris JM, de Veer SJ, Craik DJ. Swedberg JE, et al. Among authors: harris jm. ACS Med Chem Lett. 2018 Nov 21;9(12):1258-1262. doi: 10.1021/acsmedchemlett.8b00422. eCollection 2018 Dec 13. ACS Med Chem Lett. 2018. PMID: 30613336 Free PMC article.

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