Young DA - Search Results

1

cAMP response element-binding (CREB) recruitment following a specific CpG demethylation leads to the elevated expression of the matrix metalloproteinase 13 in human articular chondrocytes and osteoarthritis.

Bui C, Barter MJ, Scott JL, Xu Y, Galler M, Reynard LN, Rowan AD, Young DA. Bui C, et al. Among authors: young da. FASEB J. 2012 Jul;26(7):3000-11. doi: 10.1096/fj.12-206367. Epub 2012 Apr 13. FASEB J. 2012. PMID: 22505473

2

Cryptic promoter activity of pBLCAT3 induced by overexpression of AP1 factors.

Hall MC, Young DA, Rowan AD, Edwards DR, Clark IM. Hall MC, et al. Among authors: young da. Biotechniques. 2002 Nov;33(5):1004, 1006, 1008. doi: 10.2144/02335bm07. Biotechniques. 2002. PMID: 12449375 Free article. No abstract available.

3

The comparative role of activator protein 1 and Smad factors in the regulation of Timp-1 and MMP-1 gene expression by transforming growth factor-beta 1.

Hall MC, Young DA, Waters JG, Rowan AD, Chantry A, Edwards DR, Clark IM. Hall MC, et al. Among authors: young da. J Biol Chem. 2003 Mar 21;278(12):10304-13. doi: 10.1074/jbc.M212334200. Epub 2003 Jan 13. J Biol Chem. 2003. PMID: 12525489 Free article.

4

Oncostatin M in combination with tumour necrosis factor {alpha} induces a chondrocyte membrane associated aggrecanase that is distinct from ADAMTS aggrecanase-1 or -2.

Hui W, Barksby HE, Young DA, Cawston TE, McKie N, Rowan AD. Hui W, et al. Among authors: young da. Ann Rheum Dis. 2005 Nov;64(11):1624-32. doi: 10.1136/ard.2004.028191. Epub 2005 May 5. Ann Rheum Dis. 2005. PMID: 15883123 Free PMC article.

5

Fibroblast activation protein alpha is expressed by chondrocytes following a pro-inflammatory stimulus and is elevated in osteoarthritis.

Milner JM, Kevorkian L, Young DA, Jones D, Wait R, Donell ST, Barksby E, Patterson AM, Middleton J, Cravatt BF, Clark IM, Rowan AD, Cawston TE. Milner JM, et al. Among authors: young da. Arthritis Res Ther. 2006;8(1):R23. doi: 10.1186/ar1877. Epub 2006 Jan 3. Arthritis Res Ther. 2006. PMID: 16507127 Free PMC article.

6

Metalloproteinase and inhibitor expression profiling of resorbing cartilage reveals pro-collagenase activation as a critical step for collagenolysis.

Milner JM, Rowan AD, Cawston TE, Young DA. Milner JM, et al. Among authors: young da. Arthritis Res Ther. 2006;8(5):R142. doi: 10.1186/ar2034. Arthritis Res Ther. 2006. PMID: 16919164 Free PMC article.

7

Collagenase gene regulation by pro-inflammatory cytokines in cartilage.

Rowan AD, Young DA. Rowan AD, et al. Among authors: young da. Front Biosci. 2007 Jan 1;12:536-50. doi: 10.2741/2080. Front Biosci. 2007. PMID: 17127315 Review.

8

Differential Toll-like receptor-dependent collagenase expression in chondrocytes.

Zhang Q, Hui W, Litherland GJ, Barter MJ, Davidson R, Darrah C, Donell ST, Clark IM, Cawston TE, Robinson JH, Rowan AD, Young DA. Zhang Q, et al. Among authors: young da. Ann Rheum Dis. 2008 Nov;67(11):1633-41. doi: 10.1136/ard.2007.079574. Epub 2008 Feb 7. Ann Rheum Dis. 2008. PMID: 18258708

9

Synergistic collagenase expression and cartilage collagenolysis are phosphatidylinositol 3-kinase/Akt signaling-dependent.

Litherland GJ, Dixon C, Lakey RL, Robson T, Jones D, Young DA, Cawston TE, Rowan AD. Litherland GJ, et al. Among authors: young da. J Biol Chem. 2008 May 23;283(21):14221-9. doi: 10.1074/jbc.M710136200. Epub 2008 Mar 10. J Biol Chem. 2008. PMID: 18332138 Free article.

10

HDAC-mediated control of ERK- and PI3K-dependent TGF-β-induced extracellular matrix-regulating genes.

Barter MJ, Pybus L, Litherland GJ, Rowan AD, Clark IM, Edwards DR, Cawston TE, Young DA. Barter MJ, et al. Among authors: young da. Matrix Biol. 2010 Sep;29(7):602-12. doi: 10.1016/j.matbio.2010.05.002. Epub 2010 May 12. Matrix Biol. 2010. PMID: 20470885

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