Jurcak JG - Search Results

1

X-ray crystallographic structure-based design of selective thienopyrazole inhibitors for interleukin-2-inducible tyrosine kinase.

McLean LR, Zhang Y, Zaidi N, Bi X, Wang R, Dharanipragada R, Jurcak JG, Gillespy TA, Zhao Z, Musick KY, Choi YM, Barrague M, Peppard J, Smicker M, Duguid M, Parkar A, Fordham J, Kominos D. McLean LR, et al. Among authors: jurcak jg. Bioorg Med Chem Lett. 2012 May 1;22(9):3296-300. doi: 10.1016/j.bmcl.2012.03.016. Epub 2012 Mar 11. Bioorg Med Chem Lett. 2012. PMID: 22464456

2

Structure-activity relationships of a series of novel (piperazinylbutyl)thiazolidinone antipsychotic agents related to 3-[4-[4-(6-fluorobenzo[b]thien-3-yl)-1-piperazinyl]butyl]-2,5,5- trimethyl-4-thiazolidinone maleate.

Hrib NJ, Jurcak JG, Bregna DE, Burgher KL, Hartman HB, Kafka S, Kerman LL, Kongsamut S, Roehr JE, Szewczak MR, Woods-Kettelberger AT, Corbett R. Hrib NJ, et al. Among authors: jurcak jg. J Med Chem. 1996 Sep 27;39(20):4044-57. doi: 10.1021/jm960268u. J Med Chem. 1996. PMID: 8831770

3

Metabolism of an atypical antipsychotic agent, 3-[4-[4-(6-fluorobenzo[b]thien-3-yl)-1-piperazinyl]butyl]-2, 5,5-trimethyl-4-thiazolidinone (HP236).

Mutlib AE, Jurcak J, Hrib N. Mutlib AE, et al. Drug Metab Dispos. 1996 Oct;24(10):1139-50. Drug Metab Dispos. 1996. PMID: 8894517

4

3-[4-[1-(6-Fluorobenzo[b]thiophen-3-yl)-4-piperazinyl]butyl]- 2,5,5-trimethyl-4-thiazolidinone: a new atypical antipsychotic agent for the treatment of schizophrenia.

Hrib NJ, Jurcak JG, Bregna DE, Dunn RW, Geyer HM 3rd, Hartman HB, Roehr JE, Rogers KL, Rush DK, Szczepanik AM, et al. Hrib NJ, et al. Among authors: jurcak jg. J Med Chem. 1992 Jul 10;35(14):2712-5. doi: 10.1021/jm00092a024. J Med Chem. 1992. PMID: 1353116 No abstract available.

5

Benzisoxazole- and benzisothiazole-3-carboxamides as potential atypical antipsychotic agents.

Hrib NJ, Jurcak JG, Burgher KL, Conway PG, Hartman HB, Kerman LL, Roehr JE, Woods AT. Hrib NJ, et al. Among authors: jurcak jg. J Med Chem. 1994 Jul 22;37(15):2308-14. doi: 10.1021/jm00041a009. J Med Chem. 1994. PMID: 7914536

6

Aminopyridine carbamic acid esters: synthesis and potential as acetylcholinesterase inhibitors and acetylcholine releasers.

Shutske GM, Tomer JD, Kapples KJ, Hrib NJ, Jurcak JG, Bores GM, Huger FP, Petko W, Smith CP. Shutske GM, et al. Among authors: jurcak jg. J Pharm Sci. 1992 Apr;81(4):380-5. doi: 10.1002/jps.2600810419. J Pharm Sci. 1992. PMID: 1501077

7

Synthesis and biological evaluation of a series of substituted N-alkoxyimides and -amides as potential atypical antipsychotic agents.

Hrib NJ, Jurcak JG, Huger FP, Errico CL, Dunn RW. Hrib NJ, et al. Among authors: jurcak jg. J Med Chem. 1991 Mar;34(3):1068-72. doi: 10.1021/jm00107a028. J Med Chem. 1991. PMID: 1672156

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