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A nonfucosylated variant of the anti-HIV-1 monoclonal antibody b12 has enhanced FcγRIIIa-mediated antiviral activity in vitro but does not improve protection against mucosal SHIV challenge in macaques.
Moldt B, Shibata-Koyama M, Rakasz EG, Schultz N, Kanda Y, Dunlop DC, Finstad SL, Jin C, Landucci G, Alpert MD, Dugast AS, Parren PW, Nimmerjahn F, Evans DT, Alter G, Forthal DN, Schmitz JE, Iida S, Poignard P, Watkins DI, Hessell AJ, Burton DR. Moldt B, et al. Among authors: evans dt. J Virol. 2012 Jun;86(11):6189-96. doi: 10.1128/JVI.00491-12. Epub 2012 Mar 28. J Virol. 2012. PMID: 22457527 Free PMC article.
Definition of five new simian immunodeficiency virus cytotoxic T-lymphocyte epitopes and their restricting major histocompatibility complex class I molecules: evidence for an influence on disease progression.
Evans DT, Jing P, Allen TM, O'Connor DH, Horton H, Venham JE, Piekarczyk M, Dzuris J, Dykhuzen M, Mitchen J, Rudersdorf RA, Pauza CD, Sette A, Bontrop RE, DeMars R, Watkins DI. Evans DT, et al. J Virol. 2000 Aug;74(16):7400-10. doi: 10.1128/jvi.74.16.7400-7410.2000. J Virol. 2000. PMID: 10906193 Free PMC article.
Reversion of CTL escape-variant immunodeficiency viruses in vivo.
Friedrich TC, Dodds EJ, Yant LJ, Vojnov L, Rudersdorf R, Cullen C, Evans DT, Desrosiers RC, Mothé BR, Sidney J, Sette A, Kunstman K, Wolinsky S, Piatak M, Lifson J, Hughes AL, Wilson N, O'Connor DH, Watkins DI. Friedrich TC, et al. Among authors: evans dt. Nat Med. 2004 Mar;10(3):275-81. doi: 10.1038/nm998. Epub 2004 Feb 15. Nat Med. 2004. PMID: 14966520
Comparison of plasma viremia and antibody responses in macaques inoculated with envelope variants of single-cycle simian immunodeficiency virus differing in infectivity and cellular tropism.
DeGottardi MQ, Lew SK, Piatak M Jr, Jia B, Feng Y, Lee SJ, Brenchley JM, Douek DC, Kodama T, Lifson JD, Evans DT. DeGottardi MQ, et al. Among authors: evans dt. J Virol. 2008 Jan;82(1):321-34. doi: 10.1128/JVI.01094-07. Epub 2007 Oct 17. J Virol. 2008. PMID: 17942538 Free PMC article.
Envelope-modified single-cycle simian immunodeficiency virus selectively enhances antibody responses and partially protects against repeated, low-dose vaginal challenge.
Alpert MD, Rahmberg AR, Neidermyer W, Ng SK, Carville A, Camp JV, Wilson RL, Piatak M Jr, Mansfield KG, Li W, Miller CJ, Lifson JD, Kozlowski PA, Evans DT. Alpert MD, et al. Among authors: evans dt. J Virol. 2010 Oct;84(20):10748-64. doi: 10.1128/JVI.00945-10. Epub 2010 Aug 11. J Virol. 2010. PMID: 20702641 Free PMC article.
142 results