Wright MW - Search Results

1

Analysis of the DNA damage produced by a platinum-acridine antitumor agent and its effects in NCI-H460 lung cancer cells.

Qiao X, Zeitany AE, Wright MW, Essader AS, Levine KE, Kucera GL, Bierbach U. Qiao X, et al. Among authors: wright mw. Metallomics. 2012 Jul;4(7):645-52. doi: 10.1039/c2mt20031g. Epub 2012 Mar 29. Metallomics. 2012. PMID: 22456976 Free PMC article.

2

Metal-intercalator-mediated self-association and one-dimensional aggregation in the structure of the excised major DNA adduct of a platinum-acridine agent.

Baruah H, Day CS, Wright MW, Bierbach U. Baruah H, et al. Among authors: wright mw. J Am Chem Soc. 2004 Apr 14;126(14):4492-3. doi: 10.1021/ja038592j. J Am Chem Soc. 2004. PMID: 15070347

3

Solution structural study of a DNA duplex containing the guanine-N7 adduct formed by a cytotoxic platinum-acridine hybrid agent.

Baruah H, Wright MW, Bierbach U. Baruah H, et al. Among authors: wright mw. Biochemistry. 2005 Apr 26;44(16):6059-70. doi: 10.1021/bi050021b. Biochemistry. 2005. PMID: 15835895

4

A non-cross-linking platinum-acridine agent with potent activity in non-small-cell lung cancer.

Ma Z, Choudhury JR, Wright MW, Day CS, Saluta G, Kucera GL, Bierbach U. Ma Z, et al. Among authors: wright mw. J Med Chem. 2008 Dec 11;51(23):7574-80. doi: 10.1021/jm800900g. J Med Chem. 2008. PMID: 19012390 Free PMC article.

5

Structure-activity relationships in platinum-acridinylthiourea conjugates: effect of the thiourea nonleaving group on drug stability, nucleobase affinity, and in vitro cytotoxicity.

Ackley MC, Barry CG, Mounce AM, Farmer MC, Springer BE, Day CS, Wright MW, Berners-Price SJ, Hess SM, Bierbach U. Ackley MC, et al. Among authors: wright mw. J Biol Inorg Chem. 2004 Jun;9(4):453-61. doi: 10.1007/s00775-004-0541-4. Epub 2004 Apr 6. J Biol Inorg Chem. 2004. PMID: 15067524

6

Guanine binding of a cytotoxic platinum-acridin-9-ylthiourea conjugate monitored by 1-D 1H and 2-D [1H,15N] NMR spectroscopy: hydrolysis is not the rate-determining step.

Guddneppanavar R, Wright MW, Tomsey AK, Bierbach U. Guddneppanavar R, et al. Among authors: wright mw. J Inorg Biochem. 2006 May;100(5-6):972-9. doi: 10.1016/j.jinorgbio.2005.12.021. Epub 2006 Feb 20. J Inorg Biochem. 2006. PMID: 16488016

7

Zirconium tetraazamacrocycle complexes display extraordinary stability and provide a new strategy for zirconium-89-based radiopharmaceutical development.

Pandya DN, Bhatt N, Yuan H, Day CS, Ehrmann BM, Wright M, Bierbach U, Wadas TJ. Pandya DN, et al. Chem Sci. 2017 Mar 1;8(3):2309-2314. doi: 10.1039/c6sc04128k. Epub 2016 Dec 13. Chem Sci. 2017. PMID: 28451334 Free PMC article.

8

Ochratoxin a forms a carbon-bonded c8-deoxyguanosine nucleoside adduct: implications for c8 reactivity by a phenolic radical.

Dai J, Wright MW, Manderville RA. Dai J, et al. Among authors: wright mw. J Am Chem Soc. 2003 Apr 2;125(13):3716-7. doi: 10.1021/ja034221r. J Am Chem Soc. 2003. PMID: 12656599

9

Multidrug resistance protein (MRP) 1 and MRP3 attenuate cytotoxic and transactivating effects of the cyclopentenone prostaglandin, 15-deoxy-Delta(12,14)prostaglandin J2 in MCF7 breast cancer cells.

Paumi CM, Wright M, Townsend AJ, Morrow CS. Paumi CM, et al. Biochemistry. 2003 May 13;42(18):5429-37. doi: 10.1021/bi027347u. Biochemistry. 2003. PMID: 12731885

10

Photochemically catalyzed reaction of ochratoxin A with D- and L-cysteine.

Brow ME, Dai J, Park G, Wright MW, Gillman IG, Manderville RA. Brow ME, et al. Among authors: wright mw. Photochem Photobiol. 2002 Dec;76(6):649-56. doi: 10.1562/0031-8655(2002)076<0649:pcrooa>2.0.co;2. Photochem Photobiol. 2002. PMID: 12511045

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