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A gene variant near ATM is significantly associated with metformin treatment response in type 2 diabetes: a replication and meta-analysis of five cohorts.
van Leeuwen N, Nijpels G, Becker ML, Deshmukh H, Zhou K, Stricker BH, Uitterlinden AG, Hofman A, van 't Riet E, Palmer CN, Guigas B, Slagboom PE, Durrington P, Calle RA, Neil A, Hitman G, Livingstone SJ, Colhoun H, Holman RR, McCarthy MI, Dekker JM, 't Hart LM, Pearson ER. van Leeuwen N, et al. Among authors: guigas b. Diabetologia. 2012 Jul;55(7):1971-7. doi: 10.1007/s00125-012-2537-x. Epub 2012 Mar 28. Diabetologia. 2012. PMID: 22453232 Free PMC article.
Gene expression analysis of mTOR pathway: association with human longevity.
Passtoors WM, Beekman M, Deelen J, van der Breggen R, Maier AB, Guigas B, Derhovanessian E, van Heemst D, de Craen AJ, Gunn DA, Pawelec G, Slagboom PE. Passtoors WM, et al. Among authors: guigas b. Aging Cell. 2013 Feb;12(1):24-31. doi: 10.1111/acel.12015. Epub 2012 Nov 23. Aging Cell. 2013. PMID: 23061800 Free article.
The CTRB1/2 locus affects diabetes susceptibility and treatment via the incretin pathway.
't Hart LM, Fritsche A, Nijpels G, van Leeuwen N, Donnelly LA, Dekker JM, Alssema M, Fadista J, Carlotti F, Gjesing AP, Palmer CN, van Haeften TW, Herzberg-Schäfer SA, Simonis-Bik AM, Houwing-Duistermaat JJ, Helmer Q, Deelen J, Guigas B, Hansen T, Machicao F, Willemsen G, Heine RJ, Kramer MH, Holst JJ, de Koning EJ, Häring HU, Pedersen O, Groop L, de Geus EJ, Slagboom PE, Boomsma DI, Eekhoff EM, Pearson ER, Diamant M. 't Hart LM, et al. Among authors: guigas b. Diabetes. 2013 Sep;62(9):3275-81. doi: 10.2337/db13-0227. Epub 2013 May 14. Diabetes. 2013. PMID: 23674605 Free PMC article. Clinical Trial.
Glucocorticoid treatment impairs microvascular function in healthy men in association with its adverse effects on glucose metabolism and blood pressure: a randomised controlled trial.
van Raalte DH, Diamant M, Ouwens DM, Ijzerman RG, Linssen MM, Guigas B, Eringa EC, Serné EH. van Raalte DH, et al. Among authors: guigas b. Diabetologia. 2013 Nov;56(11):2383-91. doi: 10.1007/s00125-013-3016-8. Epub 2013 Aug 11. Diabetologia. 2013. PMID: 23933953 Clinical Trial.
Sex-specific effects of naturally occurring variants in the dopamine receptor D2 locus on insulin secretion and type 2 diabetes susceptibility.
Guigas B, de Leeuw van Weenen JE, van Leeuwen N, Simonis-Bik AM, van Haeften TW, Nijpels G, Houwing-Duistermaat JJ, Beekman M, Deelen J, Havekes LM, Penninx BW, Vogelzangs N, van 't Riet E, Dehghan A, Hofman A, Witteman JC, Uitterlinden AG, Grarup N, Jørgensen T, Witte DR, Lauritzen T, Hansen T, Pedersen O, Hottenga J, Romijn JA, Diamant M, Kramer MH, Heine RJ, Willemsen G, Dekker JM, Eekhoff EM, Pijl H, de Geus EJ, Slagboom PE, 't Hart LM. Guigas B, et al. Diabet Med. 2014 Aug;31(8):1001-8. doi: 10.1111/dme.12464. Epub 2014 May 2. Diabet Med. 2014. PMID: 24724616
Middle-aged overweight South Asian men exhibit a different metabolic adaptation to short-term energy restriction compared with Europeans.
Bakker LE, Guigas B, van Schinkel LD, van der Zon GC, Streefland TC, van Klinken JB, Jonker JT, Lamb HJ, Smit JW, Pijl H, Meinders AE, Jazet IM. Bakker LE, et al. Among authors: guigas b. Diabetologia. 2015 Jan;58(1):165-77. doi: 10.1007/s00125-014-3408-4. Epub 2014 Oct 15. Diabetologia. 2015. PMID: 25316433 Clinical Trial.
Metformin: from mechanisms of action to therapies.
Foretz M, Guigas B, Bertrand L, Pollak M, Viollet B. Foretz M, et al. Among authors: guigas b. Cell Metab. 2014 Dec 2;20(6):953-66. doi: 10.1016/j.cmet.2014.09.018. Epub 2014 Oct 30. Cell Metab. 2014. PMID: 25456737 Free article. Review.
120 results