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Identification of small-molecule inhibitors of the colorectal cancer oncogene Krüppel-like factor 5 expression by ultrahigh-throughput screening.
Bialkowska AB, Crisp M, Bannister T, He Y, Chowdhury S, Schürer S, Chase P, Spicer T, Madoux F, Tian C, Hodder P, Zaharevitz D, Yang VW. Bialkowska AB, et al. Mol Cancer Ther. 2011 Nov;10(11):2043-51. doi: 10.1158/1535-7163.MCT-11-0550. Epub 2011 Sep 1. Mol Cancer Ther. 2011. PMID: 21885866 Free PMC article.
Identification of potent inhibitors of the Trypanosoma brucei methionyl-tRNA synthetase via high-throughput orthogonal screening.
Pedró-Rosa L, Buckner FS, Ranade RM, Eberhart C, Madoux F, Gillespie JR, Koh CY, Brown S, Lohse J, Verlinde CL, Fan E, Bannister T, Scampavia L, Hol WG, Spicer T, Hodder P. Pedró-Rosa L, et al. J Biomol Screen. 2015 Jan;20(1):122-30. doi: 10.1177/1087057114548832. Epub 2014 Aug 27. J Biomol Screen. 2015. PMID: 25163684 Free PMC article.
Selective Targeting of Extracellular Insulin-Degrading Enzyme by Quasi-Irreversible Thiol-Modifying Inhibitors.
Abdul-Hay SO, Bannister TD, Wang H, Cameron MD, Caulfield TR, Masson A, Bertrand J, Howard EA, McGuire MP, Crisafulli U, Rosenberry TR, Topper CL, Thompson CR, Schürer SC, Madoux F, Hodder P, Leissring MA. Abdul-Hay SO, et al. Among authors: bannister td. ACS Chem Biol. 2015 Dec 18;10(12):2716-24. doi: 10.1021/acschembio.5b00334. Epub 2015 Sep 30. ACS Chem Biol. 2015. PMID: 26398879 Free PMC article.
Receptor antagonism/agonism can be uncoupled from pharmacoperone activity.
Janovick JA, Spicer TP, Smith E, Bannister TD, Kenakin T, Scampavia L, Conn PM. Janovick JA, et al. Among authors: bannister td. Mol Cell Endocrinol. 2016 Oct 15;434:176-85. doi: 10.1016/j.mce.2016.07.003. Epub 2016 Jul 4. Mol Cell Endocrinol. 2016. PMID: 27389877 Free PMC article.
66 results