Thatcher GR - Search Results

1

Furoxans (1,2,5-oxadiazole-N-oxides) as novel NO mimetic neuroprotective and procognitive agents.

Schiefer IT, VandeVrede L, Fa' M, Arancio O, Thatcher GR. Schiefer IT, et al. Among authors: thatcher gr. J Med Chem. 2012 Apr 12;55(7):3076-87. doi: 10.1021/jm201504s. Epub 2012 Mar 30. J Med Chem. 2012. PMID: 22429006 Free PMC article.

2

Nitric oxide mimetic molecules as therapeutic agents in Alzheimer's disease.

Thatcher GR, Bennett BM, Reynolds JN. Thatcher GR, et al. Curr Alzheimer Res. 2005 Apr;2(2):171-82. doi: 10.2174/1567205053585945. Curr Alzheimer Res. 2005. PMID: 15974915 Review.

3

An introduction to NO-related therapeutic agents.

Thatcher GR. Thatcher GR. Curr Top Med Chem. 2005;5(7):597-601. doi: 10.2174/1568026054679281. Curr Top Med Chem. 2005. PMID: 16101422 Review.

4

Benzothiophene selective estrogen receptor modulators with modulated oxidative activity and receptor affinity.

Qin Z, Kastrati I, Chandrasena RE, Liu H, Yao P, Petukhov PA, Bolton JL, Thatcher GR. Qin Z, et al. Among authors: thatcher gr. J Med Chem. 2007 May 31;50(11):2682-92. doi: 10.1021/jm070079j. Epub 2007 May 10. J Med Chem. 2007. PMID: 17489582

5

Molecular modeling, synthesis, and activity studies of novel biaryl and fused-ring BACE1 inhibitors.

Chirapu SR, Pachaiyappan B, Nural HF, Cheng X, Yuan H, Lankin DC, Abdul-Hay SO, Thatcher GR, Shen Y, Kozikowski AP, Petukhov PA. Chirapu SR, et al. Among authors: thatcher gr. Bioorg Med Chem Lett. 2009 Jan 1;19(1):264-74. doi: 10.1016/j.bmcl.2008.10.096. Epub 2008 Oct 25. Bioorg Med Chem Lett. 2009. PMID: 19013792 Free PMC article.

6

Click synthesis of estradiol-cyclodextrin conjugates as cell compartment selective estrogens.

Kim HY, Sohn J, Wijewickrama GT, Edirisinghe P, Gherezghiher T, Hemachandra M, Lu PY, Chandrasena RE, Molloy ME, Tonetti DA, Thatcher GR. Kim HY, et al. Among authors: thatcher gr. Bioorg Med Chem. 2010 Jan 15;18(2):809-21. doi: 10.1016/j.bmc.2009.11.046. Epub 2009 Nov 27. Bioorg Med Chem. 2010. PMID: 20031420 Free PMC article.

7

Proteomic and mass spectroscopic quantitation of protein S-nitrosation differentiates NO-donors.

Sinha V, Wijewickrama GT, Chandrasena RE, Xu H, Edirisinghe PD, Schiefer IT, Thatcher GR. Sinha V, et al. Among authors: thatcher gr. ACS Chem Biol. 2010 Jul 16;5(7):667-80. doi: 10.1021/cb100054m. ACS Chem Biol. 2010. PMID: 20524644 Free PMC article.

8

Inhibition of amyloidogenesis by nonsteroidal anti-inflammatory drugs and their hybrid nitrates.

Schiefer IT, Abdul-Hay S, Wang H, Vanni M, Qin Z, Thatcher GR. Schiefer IT, et al. Among authors: thatcher gr. J Med Chem. 2011 Apr 14;54(7):2293-306. doi: 10.1021/jm101450p. Epub 2011 Mar 15. J Med Chem. 2011. PMID: 21405086 Free PMC article.

9

Benzothiophene Selective Estrogen Receptor Modulators Provide Neuroprotection by a novel GPR30-dependent Mechanism.

Abdelhamid R, Luo J, Vandevrede L, Kundu I, Michalsen B, Litosh VA, Schiefer IT, Gherezghiher T, Yao P, Qin Z, Thatcher GR. Abdelhamid R, et al. Among authors: thatcher gr. ACS Chem Neurosci. 2011 May 18;2(5):256-268. doi: 10.1021/cn100106a. ACS Chem Neurosci. 2011. PMID: 21731800 Free PMC article.

10

NO-SSRIs: Nitric Oxide Chimera Drugs Incorporating a Selective Serotonin Reuptake Inhibitor.

Abdul-Hay S, Schiefer IT, Chandrasena RE, Li M, Abdelhamid R, Wang YT, Tavassoli E, Michalsen B, Asghodom RT, Luo J, Thatcher GR. Abdul-Hay S, et al. Among authors: thatcher gr. ACS Med Chem Lett. 2011 Sep 8;2(9):656-661. doi: 10.1021/ml2000033. ACS Med Chem Lett. 2011. PMID: 21927645 Free PMC article.

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