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PDGF-induced migration of vascular smooth muscle cells is inhibited by heme oxygenase-1 via VEGFR2 upregulation and subsequent assembly of inactive VEGFR2/PDGFRβ heterodimers.
Cheng C, Haasdijk RA, Tempel D, den Dekker WK, Chrifi I, Blonden LA, van de Kamp EH, de Boer M, Bürgisser PE, Noorderloos A, Rens JA, ten Hagen TL, Duckers HJ. Cheng C, et al. Among authors: noorderloos a. Arterioscler Thromb Vasc Biol. 2012 May;32(5):1289-98. doi: 10.1161/ATVBAHA.112.245530. Epub 2012 Mar 15. Arterioscler Thromb Vasc Biol. 2012. PMID: 22426130