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PDGF-induced migration of vascular smooth muscle cells is inhibited by heme oxygenase-1 via VEGFR2 upregulation and subsequent assembly of inactive VEGFR2/PDGFRβ heterodimers.
Cheng C, Haasdijk RA, Tempel D, den Dekker WK, Chrifi I, Blonden LA, van de Kamp EH, de Boer M, Bürgisser PE, Noorderloos A, Rens JA, ten Hagen TL, Duckers HJ. Cheng C, et al. Arterioscler Thromb Vasc Biol. 2012 May;32(5):1289-98. doi: 10.1161/ATVBAHA.112.245530. Epub 2012 Mar 15. Arterioscler Thromb Vasc Biol. 2012. PMID: 22426130
Large variations in absolute wall shear stress levels within one species and between species.
Cheng C, Helderman F, Tempel D, Segers D, Hierck B, Poelmann R, van Tol A, Duncker DJ, Robbers-Visser D, Ursem NT, van Haperen R, Wentzel JJ, Gijsen F, van der Steen AF, de Crom R, Krams R. Cheng C, et al. Atherosclerosis. 2007 Dec;195(2):225-35. doi: 10.1016/j.atherosclerosis.2006.11.019. Epub 2006 Dec 12. Atherosclerosis. 2007. PMID: 17169362 Review.
Rapamycin modulates the eNOS vs. shear stress relationship.
Cheng C, Tempel D, Oostlander A, Helderman F, Gijsen F, Wentzel J, van Haperen R, Haitsma DB, Serruys PW, van der Steen AF, de Crom R, Krams R. Cheng C, et al. Cardiovasc Res. 2008 Apr 1;78(1):123-9. doi: 10.1093/cvr/cvm103. Epub 2007 Dec 13. Cardiovasc Res. 2008. PMID: 18079107
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