Yang L - Search Results

1

LYP inhibits T-cell activation when dissociated from CSK.

Vang T, Liu WH, Delacroix L, Wu S, Vasile S, Dahl R, Yang L, Musumeci L, Francis D, Landskron J, Tasken K, Tremblay ML, Lie BA, Page R, Mustelin T, Rahmouni S, Rickert RC, Tautz L. Vang T, et al. Among authors: yang l. Nat Chem Biol. 2012 Mar 18;8(5):437-46. doi: 10.1038/nchembio.916. Nat Chem Biol. 2012. PMID: 22426112 Free PMC article.

2

Inhibition of hematopoietic protein tyrosine phosphatase augments and prolongs ERK1/2 and p38 activation.

Sergienko E, Xu J, Liu WH, Dahl R, Critton DA, Su Y, Brown BT, Chan X, Yang L, Bobkova EV, Vasile S, Yuan H, Rascon J, Colayco S, Sidique S, Cosford ND, Chung TD, Mustelin T, Page R, Lombroso PJ, Tautz L. Sergienko E, et al. Among authors: yang l. ACS Chem Biol. 2012 Feb 17;7(2):367-77. doi: 10.1021/cb2004274. Epub 2011 Nov 17. ACS Chem Biol. 2012. PMID: 22070201 Free PMC article.

3

A gatekeeper residue for NEDD8-activating enzyme inhibition by MLN4924.

Toth JI, Yang L, Dahl R, Petroski MD. Toth JI, et al. Among authors: yang l. Cell Rep. 2012 Apr 19;1(4):309-16. doi: 10.1016/j.celrep.2012.02.006. Epub 2012 Mar 19. Cell Rep. 2012. PMID: 22832224 Free PMC article.

4

Design, synthesis, and structure-activity relationship studies of thiophene-3-carboxamide derivatives as dual inhibitors of the c-Jun N-terminal kinase.

De SK, Barile E, Chen V, Stebbins JL, Cellitti JF, Machleidt T, Carlson CB, Yang L, Dahl R, Pellecchia M. De SK, et al. Among authors: yang l. Bioorg Med Chem. 2011 Apr 15;19(8):2582-8. doi: 10.1016/j.bmc.2011.03.017. Epub 2011 Mar 12. Bioorg Med Chem. 2011. PMID: 21458276 Free PMC article.

5

BI-97C1, an optically pure Apogossypol derivative as pan-active inhibitor of antiapoptotic B-cell lymphoma/leukemia-2 (Bcl-2) family proteins.

Wei J, Stebbins JL, Kitada S, Dash R, Placzek W, Rega MF, Wu B, Cellitti J, Zhai D, Yang L, Dahl R, Fisher PB, Reed JC, Pellecchia M. Wei J, et al. Among authors: yang l. J Med Chem. 2010 May 27;53(10):4166-76. doi: 10.1021/jm1001265. J Med Chem. 2010. PMID: 20443627 Free PMC article.

6

Design, synthesis, and structure-activity relationships of 3-ethynyl-1H-indazoles as inhibitors of the phosphatidylinositol 3-kinase signaling pathway.

Barile E, De SK, Carlson CB, Chen V, Knutzen C, Riel-Mehan M, Yang L, Dahl R, Chiang G, Pellecchia M. Barile E, et al. Among authors: yang l. J Med Chem. 2010 Dec 9;53(23):8368-75. doi: 10.1021/jm100825h. Epub 2010 Nov 9. J Med Chem. 2010. PMID: 21062009 Free PMC article.

7

Apogossypol derivatives as pan-active inhibitors of antiapoptotic B-cell lymphoma/leukemia-2 (Bcl-2) family proteins.

Wei J, Kitada S, Rega MF, Stebbins JL, Zhai D, Cellitti J, Yuan H, Emdadi A, Dahl R, Zhang Z, Yang L, Reed JC, Pellecchia M. Wei J, et al. Among authors: yang l. J Med Chem. 2009 Jul 23;52(14):4511-23. doi: 10.1021/jm900472s. J Med Chem. 2009. PMID: 19555126 Free PMC article.

8

Synthesis and optimization of thiadiazole derivatives as a novel class of substrate competitive c-Jun N-terminal kinase inhibitors.

De SK, Chen V, Stebbins JL, Chen LH, Cellitti JF, Machleidt T, Barile E, Riel-Mehan M, Dahl R, Yang L, Emdadi A, Murphy R, Pellecchia M. De SK, et al. Among authors: yang l. Bioorg Med Chem. 2010 Jan 15;18(2):590-6. doi: 10.1016/j.bmc.2009.12.013. Epub 2009 Dec 11. Bioorg Med Chem. 2010. PMID: 20045647 Free PMC article.

9

Synthesis and biological evaluation of Apogossypolone derivatives as pan-active inhibitors of antiapoptotic B-cell lymphoma/leukemia-2 (Bcl-2) family proteins.

Wei J, Kitada S, Stebbins JL, Placzek W, Zhai D, Wu B, Rega MF, Zhang Z, Cellitti J, Yang L, Dahl R, Reed JC, Pellecchia M. Wei J, et al. Among authors: yang l. J Med Chem. 2010 Nov 25;53(22):8000-11. doi: 10.1021/jm100746q. Epub 2010 Oct 29. J Med Chem. 2010. PMID: 21033669 Free PMC article.

10

An optically pure apogossypolone derivative as potent pan-active inhibitor of anti-apoptotic bcl-2 family proteins.

Wei J, Stebbins JL, Kitada S, Dash R, Zhai D, Placzek WJ, Wu B, Rega MF, Zhang Z, Barile E, Yang L, Dahl R, Fisher PB, Reed JC, Pellecchia M. Wei J, et al. Among authors: yang l. Front Oncol. 2011 Sep 30;1:28. doi: 10.3389/fonc.2011.00028. eCollection 2011. Front Oncol. 2011. PMID: 22655238 Free PMC article.

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