Mosley RT - Search Results

1

Inhibition of hepatitis C virus NS5A by fluoro-olefin based γ-turn mimetics.

Chang W, Mosley RT, Bansal S, Keilman M, Lam AM, Furman PA, Otto MJ, Sofia MJ. Chang W, et al. Among authors: mosley rt. Bioorg Med Chem Lett. 2012 Apr 15;22(8):2938-42. doi: 10.1016/j.bmcl.2012.02.051. Epub 2012 Feb 28. Bioorg Med Chem Lett. 2012. PMID: 22425564

2

Phenylpropenamide derivatives: anti-hepatitis B virus activity of the Z isomer, SAR and the search for novel analogs.

Wang P, Naduthambi D, Mosley RT, Niu C, Furman PA, Otto MJ, Sofia MJ. Wang P, et al. Among authors: mosley rt. Bioorg Med Chem Lett. 2011 Aug 1;21(15):4642-7. doi: 10.1016/j.bmcl.2011.05.077. Epub 2011 Jun 6. Bioorg Med Chem Lett. 2011. PMID: 21704526

3

Nucleoside, nucleotide, and non-nucleoside inhibitors of hepatitis C virus NS5B RNA-dependent RNA-polymerase.

Sofia MJ, Chang W, Furman PA, Mosley RT, Ross BS. Sofia MJ, et al. Among authors: mosley rt. J Med Chem. 2012 Mar 22;55(6):2481-531. doi: 10.1021/jm201384j. Epub 2012 Jan 23. J Med Chem. 2012. PMID: 22185586 Review. No abstract available.

4

Structure of hepatitis C virus polymerase in complex with primer-template RNA.

Mosley RT, Edwards TE, Murakami E, Lam AM, Grice RL, Du J, Sofia MJ, Furman PA, Otto MJ. Mosley RT, et al. J Virol. 2012 Jun;86(12):6503-11. doi: 10.1128/JVI.00386-12. Epub 2012 Apr 11. J Virol. 2012. PMID: 22496223 Free PMC article.

5

Use of 2'-spirocyclic ethers in HCV nucleoside design.

Du J, Chun BK, Mosley RT, Bansal S, Bao H, Espiritu C, Lam AM, Murakami E, Niu C, Micolochick Steuer HM, Furman PA, Sofia MJ. Du J, et al. Among authors: mosley rt. J Med Chem. 2014 Mar 13;57(5):1826-35. doi: 10.1021/jm401224y. Epub 2013 Oct 18. J Med Chem. 2014. PMID: 24079820

6

Discovery of a novel class of potent HCV NS4B inhibitors: SAR studies on piperazinone derivatives.

Kakarla R, Liu J, Naduthambi D, Chang W, Mosley RT, Bao D, Steuer HM, Keilman M, Bansal S, Lam AM, Seibel W, Neilson S, Furman PA, Sofia MJ. Kakarla R, et al. Among authors: mosley rt. J Med Chem. 2014 Mar 13;57(5):2136-60. doi: 10.1021/jm4012643. Epub 2014 Jan 29. J Med Chem. 2014. PMID: 24476391

7

Adenosine deaminase-like protein 1 (ADAL1): characterization and substrate specificity in the hydrolysis of N(6)- or O(6)-substituted purine or 2-aminopurine nucleoside monophosphates.

Murakami E, Bao H, Mosley RT, Du J, Sofia MJ, Furman PA. Murakami E, et al. Among authors: mosley rt. J Med Chem. 2011 Aug 25;54(16):5902-14. doi: 10.1021/jm200650j. Epub 2011 Jul 22. J Med Chem. 2011. PMID: 21755941

8

Molecular and structural basis for the roles of hepatitis C virus polymerase NS5B amino acids 15, 223, and 321 in viral replication and drug resistance.

Lam AM, Edwards TE, Mosley RT, Murakami E, Bansal S, Lugo C, Bao H, Otto MJ, Sofia MJ, Furman PA. Lam AM, et al. Among authors: mosley rt. Antimicrob Agents Chemother. 2014 Nov;58(11):6861-9. doi: 10.1128/AAC.03847-14. Epub 2014 Sep 2. Antimicrob Agents Chemother. 2014. PMID: 25182647 Free PMC article.

9

Correction to Nucleoside, Nucleotide, and Non-Nucleoside Inhibitors of Hepatitis C Virus NS5B RNA-Dependent RNA-Polymerase.

Sofia MJ, Chang W, Furman PA, Mosley RT, Ross BS. Sofia MJ, et al. Among authors: mosley rt. J Med Chem. 2017 Apr 13;60(7):3219. doi: 10.1021/acs.jmedchem.7b00427. Epub 2017 Mar 24. J Med Chem. 2017. PMID: 28339203 No abstract available.

10

Estrogen receptor ligands. Part 16: 2-Aryl indoles as highly subtype selective ligands for ERalpha.

Dykstra KD, Guo L, Birzin ET, Chan W, Yang YT, Hayes EC, DaSilva CA, Pai LY, Mosley RT, Kraker B, Fitzgerald PM, DiNinno F, Rohrer SP, Schaeffer JM, Hammond ML. Dykstra KD, et al. Among authors: mosley rt. Bioorg Med Chem Lett. 2007 Apr 15;17(8):2322-8. doi: 10.1016/j.bmcl.2007.01.054. Epub 2007 Jan 25. Bioorg Med Chem Lett. 2007. PMID: 17289385

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