Ijzerman AP - Search Results

1

Novel 3,6,7-substituted pyrazolopyrimidines as positive allosteric modulators for the hydroxycarboxylic acid receptor 2 (GPR109A).

Blad CC, van Veldhoven JP, Klopman C, Wolfram DR, Brussee J, Lane JR, Ijzerman AP. Blad CC, et al. Among authors: ijzerman ap. J Med Chem. 2012 Apr 12;55(7):3563-7. doi: 10.1021/jm300164q. Epub 2012 Mar 27. J Med Chem. 2012. PMID: 22420767

2

A steric and electrostatic comparison of three models for the agonist/antagonist binding site on the adenosine A1 receptor.

van der Wenden EM, Ijzerman AP, Soudijn W. van der Wenden EM, et al. Among authors: ijzerman ap. J Med Chem. 1992 Feb 21;35(4):629-35. doi: 10.1021/jm00082a003. J Med Chem. 1992. PMID: 1542091

3

Hybrid cholecystokinin-A antagonists based on molecular modeling of lorglumide and L-364,718.

van der Bent A, Blommaert AG, Melman CT, IJzerman AP, van Wijngaarden I, Soudijn W. van der Bent A, et al. Among authors: ijzerman ap. J Med Chem. 1992 Mar 20;35(6):1042-9. doi: 10.1021/jm00084a009. J Med Chem. 1992. PMID: 1552499

4

1H-imidazo[4,5-c]quinolin-4-amines: novel non-xanthine adenosine antagonists.

van Galen PJ, Nissen P, van Wijngaarden I, IJzerman AP, Soudijn W. van Galen PJ, et al. Among authors: ijzerman ap. J Med Chem. 1991 Mar;34(3):1202-6. doi: 10.1021/jm00107a046. J Med Chem. 1991. PMID: 2002461

5

A model for the antagonist binding site on the adenosine A1 receptor, based on steric, electrostatic, and hydrophobic properties.

van Galen PJ, van Vlijmen HW, IJzerman AP, Soudijn W. van Galen PJ, et al. Among authors: ijzerman ap. J Med Chem. 1990 Jun;33(6):1708-13. doi: 10.1021/jm00168a027. J Med Chem. 1990. PMID: 2342066

6

Ribose-modified adenosine analogues as potential partial agonists for the adenosine receptor.

van der Wenden EM, von Frijtag Drabbe Künzel JK, Mathôt RA, Danhof M, IJzerman AP, Soudijn W. van der Wenden EM, et al. Among authors: ijzerman ap. J Med Chem. 1995 Sep 29;38(20):4000-6. doi: 10.1021/jm00020a014. J Med Chem. 1995. PMID: 7562934

7

N4-unsubstituted N1-arylpiperazines as high-affinity 5-HT1A receptor ligands.

Kuipers W, van Wijngaarden I, Kruse CG, ter Horst-van Amstel M, Tulp MT, IJzerman AP. Kuipers W, et al. Among authors: ijzerman ap. J Med Chem. 1995 May 26;38(11):1942-54. doi: 10.1021/jm00011a014. J Med Chem. 1995. PMID: 7783126

8

N6,C8-distributed adenosine derivatives as partial agonists for adenosine A1 receptors.

Roelen H, Veldman N, Spek AL, von Frijtag Drabbe Künzel J, Mathôt RA, IJzerman AP. Roelen H, et al. Among authors: ijzerman ap. J Med Chem. 1996 Mar 29;39(7):1463-71. doi: 10.1021/jm950267m. J Med Chem. 1996. PMID: 8691477

9

5-HT1A-versus D2-receptor selectivity of flesinoxan and analogous N4-substituted N1-arylpiperazines.

Kuipers W, Kruse CG, van Wijngaarden I, Standaar PJ, Tulp MT, Veldman N, Spek AL, IJzerman AP. Kuipers W, et al. Among authors: ijzerman ap. J Med Chem. 1997 Jan 31;40(3):300-12. doi: 10.1021/jm960496o. J Med Chem. 1997. PMID: 9022796

10

N6-cyclopentyl-3'-substituted-xylofuranosyladenosines: a new class of non-xanthine adenosine A1 receptor antagonists.

Van Calenbergh S, von Frijtag Drabbe Künzel JK, Blaton NM, Peeters OM, Rozenski J, Van Aerschot A, De Bruyn A, De Keukeleire D, IJzerman AP, Herdewijn P. Van Calenbergh S, et al. Among authors: ijzerman ap. J Med Chem. 1997 Nov 7;40(23):3765-72. doi: 10.1021/jm970176k. J Med Chem. 1997. PMID: 9371242

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