Williams AC - Search Results

1

Colorectal carcinogenesis: sequential steps in the in vitro immortalization and transformation of human colonic epithelial cells (review).

Paraskeva C, Corfield AP, Harper S, Hague A, Audcent K, Williams AC. Paraskeva C, et al. Among authors: williams ac. Anticancer Res. 1990 Sep-Oct;10(5A):1189-200. Anticancer Res. 1990. PMID: 2241098 Review.

2

A single human colonic adenoma cell line can be converted in vitro to both a colorectal adenocarcinoma and a mucinous carcinoma.

Paraskeva C, Hague A, Rooney N, Williams AC, Harper SJ, Hanlon KA, Atkinson RJ, Corfield AP. Paraskeva C, et al. Among authors: williams ac. Int J Cancer. 1992 Jun 19;51(4):661-4. doi: 10.1002/ijc.2910510426. Int J Cancer. 1992. PMID: 1318272

3

Cell and molecular biology of gastrointestinal tract cancer.

Paraskeva C, Williams AC. Paraskeva C, et al. Among authors: williams ac. Curr Opin Oncol. 1992 Aug;4(4):707-13. doi: 10.1097/00001622-199208000-00017. Curr Opin Oncol. 1992. PMID: 1324739 Review.

4

Specific cytogenetic abnormalities and k-ras mutation in two new human colorectal-adenoma-derived cell lines.

Williams AC, Harper SJ, Marshall CJ, Gill RW, Mountford RA, Paraskeva C. Williams AC, et al. Int J Cancer. 1992 Nov 11;52(5):785-90. doi: 10.1002/ijc.2910520519. Int J Cancer. 1992. PMID: 1428233

5

Promotability and tissue specificity of hereditary cancer genes: do hereditary cancer patients have a reduced requirement for tumor promotion because all their somatic cells are heterozygous at the predisposing locus?

Paraskeva C, Williams AC. Paraskeva C, et al. Among authors: williams ac. Mol Carcinog. 1992;5(1):4-8. doi: 10.1002/mc.2940050104. Mol Carcinog. 1992. PMID: 1543540 Review. No abstract available.

6

Relationship between the secretion of cysteine proteinases and their inhibitors and malignant potential.

van der Stappen JW, Paraskeva C, Williams AC, Hague A, Maciewicz RA. van der Stappen JW, et al. Among authors: williams ac. Biochem Soc Trans. 1991 Nov;19(4):362S. doi: 10.1042/bst019362s. Biochem Soc Trans. 1991. PMID: 1794497 No abstract available.

7

Differential sensitivity of human colonic adenoma and carcinoma cells to transforming growth factor beta (TGF-beta): conversion of an adenoma cell line to a tumorigenic phenotype is accompanied by a reduced response to the inhibitory effects of TGF-beta.

Manning AM, Williams AC, Game SM, Paraskeva C. Manning AM, et al. Among authors: williams ac. Oncogene. 1991 Aug;6(8):1471-6. Oncogene. 1991. PMID: 1886718

8

Are different events involved in the development of sporadic versus hereditary tumours? The possible importance of the microenvironment in hereditary cancer.

Paraskeva C, Williams AC. Paraskeva C, et al. Among authors: williams ac. Br J Cancer. 1990 Jun;61(6):828-30. doi: 10.1038/bjc.1990.185. Br J Cancer. 1990. PMID: 2164833 Free PMC article. No abstract available.

9

Neoplastic transformation of a human colonic epithelial cell line: in vitro evidence for the adenoma to carcinoma sequence.

Williams AC, Harper SJ, Paraskeva C. Williams AC, et al. Cancer Res. 1990 Aug 1;50(15):4724-30. Cancer Res. 1990. PMID: 2369746

10

Mutant p53 is not fully dominant over endogenous wild type p53 in a colorectal adenoma cell line as demonstrated by induction of MDM2 protein and retention of a p53 dependent G1 arrest after gamma irradiation.

Williams AC, Miller JC, Collard TJ, Bracey TS, Cosulich S, Paraskeva C. Williams AC, et al. Oncogene. 1995 Jul 6;11(1):141-9. Oncogene. 1995. PMID: 7624121

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