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Page 1
Thiadiazoles as new inhibitors of diacylglycerol acyltransferase type 1.
Mougenot P, Namane C, Fett E, Camy F, Dadji-Faïhun R, Langot G, Monseau C, Onofri B, Pacquet F, Pascal C, Crespin O, Ben-Hassine M, Ragot JL, Van-Pham T, Philippo C, Chatelain-Egger F, Péron P, Le Bail JC, Guillot E, Chamiot-Clerc P, Chabanaud MA, Pruniaux MP, Schmidt F, Venier O, Nicolaï E, Viviani F. Mougenot P, et al. Among authors: dadji faihun r. Bioorg Med Chem Lett. 2012 Apr 1;22(7):2497-502. doi: 10.1016/j.bmcl.2012.02.006. Epub 2012 Feb 15. Bioorg Med Chem Lett. 2012. PMID: 22405833
Pyrrolidine-pyrazole ureas as potent and selective inhibitors of 11β-hydroxysteroid-dehydrogenase type 1.
Venier O, Pascal C, Braun A, Namane C, Mougenot P, Crespin O, Pacquet F, Mougenot C, Monseau C, Onofri B, Dadji-Faïhun R, Leger C, Ben-Hassine M, Van-Pham T, Ragot JL, Philippo C, Güssregen S, Engel C, Farjot G, Noah L, Maniani K, Nicolaï E. Venier O, et al. Among authors: dadji faihun r. Bioorg Med Chem Lett. 2011 Apr 15;21(8):2244-51. doi: 10.1016/j.bmcl.2011.02.111. Epub 2011 Mar 23. Bioorg Med Chem Lett. 2011. PMID: 21439819
Discovery of SAR184841, a potent and long-lasting inhibitor of 11β-hydroxysteroid dehydrogenase type 1, active in a physiopathological animal model of T2D.
Venier O, Pascal C, Braun A, Namane C, Mougenot P, Crespin O, Pacquet F, Mougenot C, Monseau C, Onofri B, Dadji-Faïhun R, Leger C, Ben-Hassine M, Van-Pham T, Ragot JL, Philippo C, Farjot G, Noah L, Maniani K, Boutarfa A, Nicolaï E, Guillot E, Pruniaux MP, Güssregen S, Engel C, Coutant AL, de Miguel B, Castro A. Venier O, et al. Among authors: dadji faihun r. Bioorg Med Chem Lett. 2013 Apr 15;23(8):2414-21. doi: 10.1016/j.bmcl.2013.02.018. Epub 2013 Feb 22. Bioorg Med Chem Lett. 2013. PMID: 23478147
Synthesis and multiparametric evaluation of thiadiazoles and oxadiazoles as diacylglycerol acyltransferase type 1 inhibitors.
Mougenot P, Namane C, Fett E, Goumy F, Dadji-Faïhun R, Langot G, Monseau C, Onofri B, Pacquet F, Pascal C, Crespin O, Ben-Hassine M, Ragot JL, Van-Pham T, Philippo C, Chatelain-Egger F, Péron P, Le Bail JC, Guillot E, Chamiot-Clerc P, Chabanaud MA, Pruniaux MP, Ménegotto J, Schmidt F, Venier O, Viviani F, Nicolai E. Mougenot P, et al. Among authors: dadji faihun r. Bioorg Med Chem Lett. 2016 Jan 1;26(1):25-32. doi: 10.1016/j.bmcl.2015.11.046. Epub 2015 Nov 25. Bioorg Med Chem Lett. 2016. PMID: 26627579