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Fumarate is cardioprotective via activation of the Nrf2 antioxidant pathway.
Ashrafian H, Czibik G, Bellahcene M, Aksentijević D, Smith AC, Mitchell SJ, Dodd MS, Kirwan J, Byrne JJ, Ludwig C, Isackson H, Yavari A, Støttrup NB, Contractor H, Cahill TJ, Sahgal N, Ball DR, Birkler RI, Hargreaves I, Tennant DA, Land J, Lygate CA, Johannsen M, Kharbanda RK, Neubauer S, Redwood C, de Cabo R, Ahmet I, Talan M, Günther UL, Robinson AJ, Viant MR, Pollard PJ, Tyler DJ, Watkins H. Ashrafian H, et al. Among authors: stottrup nb. Cell Metab. 2012 Mar 7;15(3):361-71. doi: 10.1016/j.cmet.2012.01.017. Cell Metab. 2012. PMID: 22405071 Free PMC article.
Remote ischemic preconditioning with--but not without--metabolic support protects the neonatal porcine heart against ischemia-reperfusion injury.
Schmidt MR, Støttrup NB, Contractor H, Hyldebrandt JA, Johannsen M, Pedersen CM, Birkler R, Ashrafian H, Sørensen KE, Kharbanda RK, Redington AN, Bøtker HE. Schmidt MR, et al. Among authors: stottrup nb. Int J Cardiol. 2014 Jan 1;170(3):388-93. doi: 10.1016/j.ijcard.2013.11.020. Epub 2013 Nov 12. Int J Cardiol. 2014. PMID: 24280512
Adenosine Receptor Activation in the "Trigger" Limb of Remote Pre-Conditioning Mediates Human Endothelial Conditioning and Release of Circulating Cardioprotective Factor(s).
Contractor H, Lie RH, Cunnington C, Li J, Støttrup NB, Manlhiot C, Bøtker HE, Schmidt MR, Forfar JC, Ashrafian H, Redington A, Kharbanda RK. Contractor H, et al. Among authors: stottrup nb. JACC Basic Transl Sci. 2016 Sep 28;1(6):461-471. doi: 10.1016/j.jacbts.2016.06.002. eCollection 2016 Oct. JACC Basic Transl Sci. 2016. PMID: 30167533 Free PMC article.
Remote ischemic preconditioning impairs ventricular function and increases infarct size after prolonged ischemia in the isolated neonatal rabbit heart.
Schmidt MR, Støttrup NB, Michelsen MM, Contractor H, Sørensen KE, Kharbanda RK, Redington AN, Bøtker HE. Schmidt MR, et al. Among authors: stottrup nb. J Thorac Cardiovasc Surg. 2014 Mar;147(3):1049-55. doi: 10.1016/j.jtcvs.2013.05.022. Epub 2013 Jul 18. J Thorac Cardiovasc Surg. 2014. PMID: 23871143 Free article.
Cardioprotection by L-glutamate during postischaemic reperfusion: reduced infarct size and enhanced glycogen resynthesis in a rat insulin-free heart model.
Kristiansen SB, Løfgren B, Støttrup NB, Kimose HH, Nielsen-Kudsk JE, Bøtker HE, Nielsen TT. Kristiansen SB, et al. Among authors: stottrup nb. Clin Exp Pharmacol Physiol. 2008 Aug;35(8):884-8. doi: 10.1111/j.1440-1681.2008.04914.x. Epub 2008 Mar 13. Clin Exp Pharmacol Physiol. 2008. PMID: 18346179
30 results