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Page 1
Atomic view of a toxic amyloid small oligomer.
Laganowsky A, Liu C, Sawaya MR, Whitelegge JP, Park J, Zhao M, Pensalfini A, Soriaga AB, Landau M, Teng PK, Cascio D, Glabe C, Eisenberg D. Laganowsky A, et al. Among authors: soriaga ab. Science. 2012 Mar 9;335(6073):1228-31. doi: 10.1126/science.1213151. Science. 2012. PMID: 22403391 Free PMC article.
Molecular mechanisms for protein-encoded inheritance.
Wiltzius JJ, Landau M, Nelson R, Sawaya MR, Apostol MI, Goldschmidt L, Soriaga AB, Cascio D, Rajashankar K, Eisenberg D. Wiltzius JJ, et al. Among authors: soriaga ab. Nat Struct Mol Biol. 2009 Sep;16(9):973-8. doi: 10.1038/nsmb.1643. Epub 2009 Aug 16. Nat Struct Mol Biol. 2009. PMID: 19684598 Free PMC article.
Molecular basis for amyloid-beta polymorphism.
Colletier JP, Laganowsky A, Landau M, Zhao M, Soriaga AB, Goldschmidt L, Flot D, Cascio D, Sawaya MR, Eisenberg D. Colletier JP, et al. Among authors: soriaga ab. Proc Natl Acad Sci U S A. 2011 Oct 11;108(41):16938-43. doi: 10.1073/pnas.1112600108. Epub 2011 Sep 23. Proc Natl Acad Sci U S A. 2011. PMID: 21949245 Free PMC article.
Atomic structure of a toxic, oligomeric segment of SOD1 linked to amyotrophic lateral sclerosis (ALS).
Sangwan S, Zhao A, Adams KL, Jayson CK, Sawaya MR, Guenther EL, Pan AC, Ngo J, Moore DM, Soriaga AB, Do TD, Goldschmidt L, Nelson R, Bowers MT, Koehler CM, Shaw DE, Novitch BG, Eisenberg DS. Sangwan S, et al. Among authors: soriaga ab. Proc Natl Acad Sci U S A. 2017 Aug 15;114(33):8770-8775. doi: 10.1073/pnas.1705091114. Epub 2017 Jul 31. Proc Natl Acad Sci U S A. 2017. PMID: 28760994 Free PMC article.
Toxicity of eosinophil MBP is repressed by intracellular crystallization and promoted by extracellular aggregation.
Soragni A, Yousefi S, Stoeckle C, Soriaga AB, Sawaya MR, Kozlowski E, Schmid I, Radonjic-Hoesli S, Boutet S, Williams GJ, Messerschmidt M, Seibert MM, Cascio D, Zatsepin NA, Burghammer M, Riekel C, Colletier JP, Riek R, Eisenberg DS, Simon HU. Soragni A, et al. Among authors: soriaga ab. Mol Cell. 2015 Mar 19;57(6):1011-1021. doi: 10.1016/j.molcel.2015.01.026. Epub 2015 Feb 26. Mol Cell. 2015. PMID: 25728769 Free PMC article.
A Designed Inhibitor of p53 Aggregation Rescues p53 Tumor Suppression in Ovarian Carcinomas.
Soragni A, Janzen DM, Johnson LM, Lindgren AG, Thai-Quynh Nguyen A, Tiourin E, Soriaga AB, Lu J, Jiang L, Faull KF, Pellegrini M, Memarzadeh S, Eisenberg DS. Soragni A, et al. Among authors: soriaga ab. Cancer Cell. 2016 Jan 11;29(1):90-103. doi: 10.1016/j.ccell.2015.12.002. Epub 2015 Dec 31. Cancer Cell. 2016. PMID: 26748848 Free PMC article.