Carracedo A - Search Results

1

Systemic elevation of PTEN induces a tumor-suppressive metabolic state.

Garcia-Cao I, Song MS, Hobbs RM, Laurent G, Giorgi C, de Boer VC, Anastasiou D, Ito K, Sasaki AT, Rameh L, Carracedo A, Vander Heiden MG, Cantley LC, Pinton P, Haigis MC, Pandolfi PP. Garcia-Cao I, et al. Among authors: carracedo a. Cell. 2012 Mar 30;149(1):49-62. doi: 10.1016/j.cell.2012.02.030. Epub 2012 Mar 6. Cell. 2012. PMID: 22401813 Free PMC article.

2

Tenets of PTEN tumor suppression.

Salmena L, Carracedo A, Pandolfi PP. Salmena L, et al. Among authors: carracedo a. Cell. 2008 May 2;133(3):403-14. doi: 10.1016/j.cell.2008.04.013. Cell. 2008. PMID: 18455982 Free article.

3

SnapShot: PTEN signaling pathways.

Carracedo A, Salmena L, Pandolfi PP. Carracedo A, et al. Cell. 2008 May 2;133(3):550.e1. doi: 10.1016/j.cell.2008.04.023. Cell. 2008. PMID: 18455993 Free article. No abstract available.

4

Aberrant Rheb-mediated mTORC1 activation and Pten haploinsufficiency are cooperative oncogenic events.

Nardella C, Chen Z, Salmena L, Carracedo A, Alimonti A, Egia A, Carver B, Gerald W, Cordon-Cardo C, Pandolfi PP. Nardella C, et al. Among authors: carracedo a. Genes Dev. 2008 Aug 15;22(16):2172-7. doi: 10.1101/gad.1699608. Genes Dev. 2008. PMID: 18708577 Free PMC article.

5

The deubiquitinylation and localization of PTEN are regulated by a HAUSP-PML network.

Song MS, Salmena L, Carracedo A, Egia A, Lo-Coco F, Teruya-Feldstein J, Pandolfi PP. Song MS, et al. Among authors: carracedo a. Nature. 2008 Oct 9;455(7214):813-7. doi: 10.1038/nature07290. Epub 2008 Aug 20. Nature. 2008. PMID: 18716620 Free PMC article.

6

Inhibition of mTORC1 leads to MAPK pathway activation through a PI3K-dependent feedback loop in human cancer.

Carracedo A, Ma L, Teruya-Feldstein J, Rojo F, Salmena L, Alimonti A, Egia A, Sasaki AT, Thomas G, Kozma SC, Papa A, Nardella C, Cantley LC, Baselga J, Pandolfi PP. Carracedo A, et al. J Clin Invest. 2008 Sep;118(9):3065-74. doi: 10.1172/JCI34739. J Clin Invest. 2008. PMID: 18725988 Free PMC article.

7

The PTEN-PI3K pathway: of feedbacks and cross-talks.

Carracedo A, Pandolfi PP. Carracedo A, et al. Oncogene. 2008 Sep 18;27(41):5527-41. doi: 10.1038/onc.2008.247. Oncogene. 2008. PMID: 18794886

8

Deconstructing feedback-signaling networks to improve anticancer therapy with mTORC1 inhibitors.

Carracedo A, Baselga J, Pandolfi PP. Carracedo A, et al. Cell Cycle. 2008 Dec 15;7(24):3805-9. doi: 10.4161/cc.7.24.7244. Epub 2008 Dec 22. Cell Cycle. 2008. PMID: 19098454 Free PMC article. Review.

9

Differential requirement of mTOR in postmitotic tissues and tumorigenesis.

Nardella C, Carracedo A, Alimonti A, Hobbs RM, Clohessy JG, Chen Z, Egia A, Fornari A, Fiorentino M, Loda M, Kozma SC, Thomas G, Cordon-Cardo C, Pandolfi PP. Nardella C, et al. Among authors: carracedo a. Sci Signal. 2009 Jan 27;2(55):ra2. doi: 10.1126/scisignal.2000189. Sci Signal. 2009. PMID: 19176516 Free PMC article.

10

Aberrant ERG expression cooperates with loss of PTEN to promote cancer progression in the prostate.

Carver BS, Tran J, Gopalan A, Chen Z, Shaikh S, Carracedo A, Alimonti A, Nardella C, Varmeh S, Scardino PT, Cordon-Cardo C, Gerald W, Pandolfi PP. Carver BS, et al. Among authors: carracedo a. Nat Genet. 2009 May;41(5):619-24. doi: 10.1038/ng.370. Epub 2009 Apr 26. Nat Genet. 2009. PMID: 19396168 Free PMC article.

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