Proliferating cell nuclear antigen (PCNA) is required for cell cycle-regulated silent chromatin on replicated and nonreplicated genes.
Miller A, Chen J, Takasuka TE, Jacobi JL, Kaufman PD, Irudayaraj JM, Kirchmaier AL.
Miller A, et al.
J Biol Chem. 2010 Nov 5;285(45):35142-54. doi: 10.1074/jbc.M110.166918. Epub 2010 Sep 2.
J Biol Chem. 2010.
PMID: 20813847
Free PMC article.
In Saccharomyces cerevisiae, silent chromatin is formed at HMR upon the passage through S phase, yet neither the initiation of DNA replication at silencers nor the passage of a replication fork through HMR is required for silencing. Paradoxically, mutations in the DNA repl …
In Saccharomyces cerevisiae, silent chromatin is formed at HMR upon the passage through S phase, yet neither the initiation of DNA replicati …