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Perfluoroalkyl sulfonates cause alkyl chain length-dependent hepatic steatosis and hypolipidemia mainly by impairing lipoprotein production in APOE*3-Leiden CETP mice.
Bijland S, Rensen PC, Pieterman EJ, Maas AC, van der Hoorn JW, van Erk MJ, Havekes LM, Willems van Dijk K, Chang SC, Ehresman DJ, Butenhoff JL, Princen HM. Bijland S, et al. Among authors: princen hm. Toxicol Sci. 2011 Sep;123(1):290-303. doi: 10.1093/toxsci/kfr142. Epub 2011 Jun 24. Toxicol Sci. 2011. PMID: 21705711
Osteoarthritis development is induced by increased dietary cholesterol and can be inhibited by atorvastatin in APOE*3Leiden.CETP mice--a translational model for atherosclerosis.
Gierman LM, Kühnast S, Koudijs A, Pieterman EJ, Kloppenburg M, van Osch GJ, Stojanovic-Susulic V, Huizinga TW, Princen HM, Zuurmond AM. Gierman LM, et al. Among authors: princen hm. Ann Rheum Dis. 2014 May;73(5):921-7. doi: 10.1136/annrheumdis-2013-203248. Epub 2013 Apr 26. Ann Rheum Dis. 2014. PMID: 23625977
Inhibition of macrophage proliferation dominates plaque regression in response to cholesterol lowering.
Härdtner C, Kornemann J, Krebs K, Ehlert CA, Jander A, Zou J, Starz C, Rauterberg S, Sharipova D, Dufner B, Hoppe N, Dederichs TS, Willecke F, Stachon P, Heidt T, Wolf D, von Zur Mühlen C, Madl J, Kohl P, Kaeser R, Boettler T, Pieterman EJ, Princen HMG, Ho-Tin-Noé B, Swirski FK, Robbins CS, Bode C, Zirlik A, Hilgendorf I. Härdtner C, et al. Basic Res Cardiol. 2020 Dec 9;115(6):78. doi: 10.1007/s00395-020-00838-4. Basic Res Cardiol. 2020. PMID: 33296022 Free PMC article.
Systemic PFOS and PFOA exposure and disturbed lipid homeostasis in humans: what do we know and what not?
Fragki S, Dirven H, Fletcher T, Grasl-Kraupp B, Bjerve Gützkow K, Hoogenboom R, Kersten S, Lindeman B, Louisse J, Peijnenburg A, Piersma AH, Princen HMG, Uhl M, Westerhout J, Zeilmaker MJ, Luijten M. Fragki S, et al. Crit Rev Toxicol. 2021 Feb;51(2):141-164. doi: 10.1080/10408444.2021.1888073. Epub 2021 Apr 15. Crit Rev Toxicol. 2021. PMID: 33853480 Free article. Review.
Variable cartilage degradation in mice with diet-induced metabolic dysfunction: food for thought.
Kozijn AE, Gierman LM, van der Ham F, Mulder P, Morrison MC, Kühnast S, van der Heijden RA, Stavro PM, van Koppen A, Pieterman EJ, van den Hoek AM, Kleemann R, Princen HMG, Mastbergen SC, Lafeber FPJG, Zuurmond AM, Bobeldijk I, Weinans H, Stoop R. Kozijn AE, et al. Osteoarthritis Cartilage. 2018 Jan;26(1):95-107. doi: 10.1016/j.joca.2017.10.010. Epub 2017 Oct 24. Osteoarthritis Cartilage. 2018. PMID: 29074298 Free article.
No effect of C-reactive protein on early atherosclerosis development in apolipoprotein E*3-leiden/human C-reactive protein transgenic mice.
Trion A, de Maat MP, Jukema JW, van der Laarse A, Maas MC, Offerman EH, Havekes LM, Szalai AJ, Princen HM, Emeis JJ. Trion A, et al. Among authors: princen hm. Arterioscler Thromb Vasc Biol. 2005 Aug;25(8):1635-40. doi: 10.1161/01.ATV.0000171992.36710.1e. Epub 2005 May 26. Arterioscler Thromb Vasc Biol. 2005. PMID: 15920036
200 results