Hruby D - Search Results

1

Evaluation of disease and viral biomarkers as triggers for therapeutic intervention in respiratory mousepox - an animal model of smallpox.

Parker S, Chen NG, Foster S, Hartzler H, Hembrador E, Hruby D, Jordan R, Lanier R, Painter G, Painter W, Sagartz JE, Schriewer J, Mark Buller R. Parker S, et al. Among authors: hruby d. Antiviral Res. 2012 Apr;94(1):44-53. doi: 10.1016/j.antiviral.2012.02.005. Epub 2012 Feb 18. Antiviral Res. 2012. PMID: 22381921 Free PMC article.

2

Smallpox antiviral drug development: satisfying the animal efficacy rule.

Jordan R, Hruby D. Jordan R, et al. Among authors: hruby d. Expert Rev Anti Infect Ther. 2006 Apr;4(2):277-89. doi: 10.1586/14787210.4.2.277. Expert Rev Anti Infect Ther. 2006. PMID: 16597208 Free PMC article. Review.

3

Evaluation of orally delivered ST-246 as postexposure prophylactic and antiviral therapeutic in an aerosolized rabbitpox rabbit model.

Nalca A, Hatkin JM, Garza NL, Nichols DK, Norris SW, Hruby DE, Jordan R. Nalca A, et al. Antiviral Res. 2008 Aug;79(2):121-7. doi: 10.1016/j.antiviral.2008.03.005. Epub 2008 Apr 23. Antiviral Res. 2008. PMID: 18479761

4

Deletion of the vaccinia virus F13L gene results in a highly attenuated virus that mounts a protective immune response against subsequent vaccinia virus challenge.

Vliegen I, Yang G, Hruby D, Jordan R, Neyts J. Vliegen I, et al. Among authors: hruby d. Antiviral Res. 2012 Jan;93(1):160-6. doi: 10.1016/j.antiviral.2011.11.010. Epub 2011 Nov 25. Antiviral Res. 2012. PMID: 22138484

5

Increased susceptibility of Cantagalo virus to the antiviral effect of ST-246®.

Santos-Fernandes É, Beltrame CO, Byrd CM, Cardwell KB, Schnellrath LC, Medaglia ML, Hruby DE, Jordan R, Damaso CR. Santos-Fernandes É, et al. Antiviral Res. 2013 Mar;97(3):301-11. doi: 10.1016/j.antiviral.2012.11.010. Epub 2012 Dec 17. Antiviral Res. 2013. PMID: 23257396 Free article.

6

Immune responses to the smallpox vaccine given in combination with ST-246, a small-molecule inhibitor of poxvirus dissemination.

Grosenbach DW, Jordan R, King DS, Berhanu A, Warren TK, Kirkwood-Watts DL, Tyavanagimatt S, Tan Y, Wilson RL, Jones KF, Hruby DE. Grosenbach DW, et al. Vaccine. 2008 Feb 13;26(7):933-46. doi: 10.1016/j.vaccine.2007.11.095. Epub 2007 Dec 26. Vaccine. 2008. PMID: 18226434 Free PMC article.

7

Efficacy of delayed treatment with ST-246 given orally against systemic orthopoxvirus infections in mice.

Quenelle DC, Buller RM, Parker S, Keith KA, Hruby DE, Jordan R, Kern ER. Quenelle DC, et al. Antimicrob Agents Chemother. 2007 Feb;51(2):689-95. doi: 10.1128/AAC.00879-06. Epub 2006 Nov 20. Antimicrob Agents Chemother. 2007. PMID: 17116683 Free PMC article.

8

Synergistic efficacy of the combination of ST-246 with CMX001 against orthopoxviruses.

Quenelle DC, Prichard MN, Keith KA, Hruby DE, Jordan R, Painter GR, Robertson A, Kern ER. Quenelle DC, et al. Antimicrob Agents Chemother. 2007 Nov;51(11):4118-24. doi: 10.1128/AAC.00762-07. Epub 2007 Aug 27. Antimicrob Agents Chemother. 2007. PMID: 17724153 Free PMC article.

9

In vitro efficacy of ST246 against smallpox and monkeypox.

Smith SK, Olson VA, Karem KL, Jordan R, Hruby DE, Damon IK. Smith SK, et al. Antimicrob Agents Chemother. 2009 Mar;53(3):1007-12. doi: 10.1128/AAC.01044-08. Epub 2008 Dec 15. Antimicrob Agents Chemother. 2009. PMID: 19075062 Free PMC article.

10

Development of the small-molecule antiviral ST-246 as a smallpox therapeutic.

Grosenbach DW, Jordan R, Hruby DE. Grosenbach DW, et al. Future Virol. 2011 May;6(5):653-671. doi: 10.2217/fvl.11.27. Future Virol. 2011. PMID: 21837250 Free PMC article.

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