Brucoli F - Search Results

1

Efficient synthesis and biological evaluation of proximicins A, B and C.

Brucoli F, Natoli A, Marimuthu P, Borrello MT, Stapleton P, Gibbons S, Schätzlein A. Brucoli F, et al. Bioorg Med Chem. 2012 Mar 15;20(6):2019-24. doi: 10.1016/j.bmc.2012.01.043. Epub 2012 Feb 4. Bioorg Med Chem. 2012. PMID: 22364744

2

Novel C8-linked pyrrolobenzodiazepine (PBD)-heterocycle conjugates that recognize DNA sequences containing an inverted CCAAT box.

Brucoli F, Hawkins RM, James CH, Wells G, Jenkins TC, Ellis T, Hartley JA, Howard PW, Thurston DE. Brucoli F, et al. Bioorg Med Chem Lett. 2011 Jun 15;21(12):3780-3. doi: 10.1016/j.bmcl.2011.04.054. Epub 2011 Apr 20. Bioorg Med Chem Lett. 2011. PMID: 21570842

3

Structural characterization and antimicrobial evaluation of atractyloside, atractyligenin, and 15-didehydroatractyligenin methyl ester.

Brucoli F, Borrello MT, Stapleton P, Parkinson GN, Gibbons S. Brucoli F, et al. J Nat Prod. 2012 Jun 22;75(6):1070-5. doi: 10.1021/np300080w. Epub 2012 May 17. J Nat Prod. 2012. PMID: 22594797

4

Synthesis, anti-mycobacterial activity and DNA sequence-selectivity of a library of biaryl-motifs containing polyamides.

Brucoli F, Guzman JD, Maitra A, James CH, Fox KR, Bhakta S. Brucoli F, et al. Bioorg Med Chem. 2015 Jul 1;23(13):3705-11. doi: 10.1016/j.bmc.2015.04.001. Epub 2015 Apr 8. Bioorg Med Chem. 2015. PMID: 25921267

5

Novel C-3-(N-alkyl-aryl)-aminomethyl rifamycin SV derivatives exhibit activity against rifampicin-resistant Mycobacterium tuberculosis RpoB_S522L strain and display a different binding mode at the RNAP β-subunit site compared to rifampicin.

Zloh M, Gupta M, Parish T, Brucoli F. Zloh M, et al. Among authors: brucoli f. Eur J Med Chem. 2021 Dec 5;225:113734. doi: 10.1016/j.ejmech.2021.113734. Epub 2021 Aug 8. Eur J Med Chem. 2021. PMID: 34418786

6

C2-linked alkynyl poly-ethylene glycol(PEG) adenosine conjugates as water-soluble adenosine receptor agonists.

Ferguson L, Madieh NS, Vaideanu A, Schatzlein A, Festa J, Singh H, Wells G, Bhakta S, Brucoli F. Ferguson L, et al. Among authors: brucoli f. Chem Biol Drug Des. 2023 Feb;101(2):340-349. doi: 10.1111/cbdd.14128. Epub 2022 Aug 22. Chem Biol Drug Des. 2023. PMID: 35993496 Free PMC article.

7

Aminobenzofuran-containing analogues of proximicins exhibit higher antiproliferative activity against human UG-87 glioblastoma cells compared to temozolomide.

Shokrzadeh Madieh N, Tanna S, Alqurayn NA, Vaideanu A, Schatzlein A, Brucoli F. Shokrzadeh Madieh N, et al. Among authors: brucoli f. RSC Adv. 2023 Mar 14;13(12):8420-8426. doi: 10.1039/d3ra00107e. eCollection 2023 Mar 8. RSC Adv. 2023. PMID: 36926006 Free PMC article.

8

Synthesis and antitubercular activity of novel 4-arylalkyl substituted thio-, oxy- and sulfoxy-quinoline analogues targeting the cytochrome bc1 complex.

Murnane R, Zloh M, Tanna S, Allen R, Santana-Gomez F, Parish T, Brucoli F. Murnane R, et al. Among authors: brucoli f. Bioorg Chem. 2023 Sep;138:106659. doi: 10.1016/j.bioorg.2023.106659. Epub 2023 Jun 7. Bioorg Chem. 2023. PMID: 37336104 Free article.

9

Efficient solid-phase synthesis of a library of distamycin analogs containing novel biaryl motifs on SynPhase Lanterns.

Brucoli F, Howard PW, Thurston DE. Brucoli F, et al. J Comb Chem. 2009 Jul-Aug;11(4):576-86. doi: 10.1021/cc900009r. J Comb Chem. 2009. PMID: 19530662

10

Synthesis and Biological Evaluation of a Novel C8-Pyrrolobenzodiazepine (PBD) Adenosine Conjugate. A Study on the Role of the PBD Ring in the Biological Activity of PBD-Conjugates.

Ferguson L, Bhakta S, Fox KR, Wells G, Brucoli F. Ferguson L, et al. Among authors: brucoli f. Molecules. 2020 Mar 10;25(5):1243. doi: 10.3390/molecules25051243. Molecules. 2020. PMID: 32164166 Free PMC article.

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