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HER2 and HLA-A*02 dual CAR-T cells utilize LOH in a NOT logic gate to address on-target off-tumor toxicity.
Bassan D, Weinberger L, Yi J, Kim T, Weist MR, Adams GB, Foord O, Chaim N, Tabak S, Bujanover N, Lopesco Y, Vucci K, Schnair C, Levy-Knafo L, Kendall RL, Calzone FJ, Sharbi-Yunger A. Bassan D, et al. Among authors: lopesco y. J Immunother Cancer. 2023 Dec 14;11(12):e007426. doi: 10.1136/jitc-2023-007426. J Immunother Cancer. 2023. PMID: 38097342 Free PMC article.