Chen CS - Search Results

1

OSU-03012 suppresses GRP78/BiP expression that causes PERK-dependent increases in tumor cell killing.

Booth L, Cazanave SC, Hamed HA, Yacoub A, Ogretmen B, Chen CS, Grant S, Dent P. Booth L, et al. Among authors: chen cs. Cancer Biol Ther. 2012 Feb 15;13(4):224-36. doi: 10.4161/cbt.13.4.18877. Cancer Biol Ther. 2012. PMID: 22354011 Free PMC article.

2

OSU-03012 promotes caspase-independent but PERK-, cathepsin B-, BID-, and AIF-dependent killing of transformed cells.

Yacoub A, Park MA, Hanna D, Hong Y, Mitchell C, Pandya AP, Harada H, Powis G, Chen CS, Koumenis C, Grant S, Dent P. Yacoub A, et al. Among authors: chen cs. Mol Pharmacol. 2006 Aug;70(2):589-603. doi: 10.1124/mol.106.025007. Epub 2006 Apr 18. Mol Pharmacol. 2006. PMID: 16622074

3

OSU-03012 stimulates PKR-like endoplasmic reticulum-dependent increases in 70-kDa heat shock protein expression, attenuating its lethal actions in transformed cells.

Park MA, Yacoub A, Rahmani M, Zhang G, Hart L, Hagan MP, Calderwood SK, Sherman MY, Koumenis C, Spiegel S, Chen CS, Graf M, Curiel DT, Fisher PB, Grant S, Dent P. Park MA, et al. Among authors: chen cs. Mol Pharmacol. 2008 Apr;73(4):1168-84. doi: 10.1124/mol.107.042697. Epub 2008 Jan 8. Mol Pharmacol. 2008. PMID: 18182481 Free PMC article.

4

PERK-dependent regulation of HSP70 expression and the regulation of autophagy.

Park MA, Curiel DT, Koumenis C, Graf M, Chen CS, Fisher PB, Grant S, Dent P. Park MA, et al. Among authors: chen cs. Autophagy. 2008 Apr;4(3):364-7. doi: 10.4161/auto.5593. Epub 2008 Jan 17. Autophagy. 2008. PMID: 18216498

5

OSU-03012 enhances Ad.7-induced GBM cell killing via ER stress and autophagy and by decreasing expression of mitochondrial protective proteins.

Hamed HA, Yacoub A, Park MA, Eulitt P, Sarkar D, Dimitrie IP, Chen CS, Grant S, Curiel DT, Fisher PB, Dent P. Hamed HA, et al. Among authors: chen cs. Cancer Biol Ther. 2010 Apr 1;9(7):526-36. doi: 10.4161/cbt.9.7.11116. Epub 2010 Apr 1. Cancer Biol Ther. 2010. PMID: 20107314 Free PMC article.

6

OSU-03012 interacts with lapatinib to kill brain cancer cells.

Booth L, Cruickshanks N, Ridder T, Chen CS, Grant S, Dent P. Booth L, et al. Among authors: chen cs. Cancer Biol Ther. 2012 Dec;13(14):1501-11. doi: 10.4161/cbt.22275. Epub 2012 Sep 18. Cancer Biol Ther. 2012. PMID: 22990204 Free PMC article.

7

Multi-kinase inhibitors can associate with heat shock proteins through their NH2-termini by which they suppress chaperone function.

Booth L, Shuch B, Albers T, Roberts JL, Tavallai M, Proniuk S, Zukiwski A, Wang D, Chen CS, Bottaro D, Ecroyd H, Lebedyeva IO, Dent P. Booth L, et al. Among authors: chen cs. Oncotarget. 2016 Mar 15;7(11):12975-96. doi: 10.18632/oncotarget.7349. Oncotarget. 2016. PMID: 26887051 Free PMC article.

8

OSU-03012, a novel celecoxib derivative, induces reactive oxygen species-related autophagy in hepatocellular carcinoma.

Gao M, Yeh PY, Lu YS, Hsu CH, Chen KF, Lee WC, Feng WC, Chen CS, Kuo ML, Cheng AL. Gao M, et al. Among authors: chen cs, chen kf. Cancer Res. 2008 Nov 15;68(22):9348-57. doi: 10.1158/0008-5472.CAN-08-1642. Cancer Res. 2008. PMID: 19010909

9

PP2A-activating drugs selectively eradicate TKI-resistant chronic myeloid leukemic stem cells.

Neviani P, Harb JG, Oaks JJ, Santhanam R, Walker CJ, Ellis JJ, Ferenchak G, Dorrance AM, Paisie CA, Eiring AM, Ma Y, Mao HC, Zhang B, Wunderlich M, May PC, Sun C, Saddoughi SA, Bielawski J, Blum W, Klisovic RB, Solt JA, Byrd JC, Volinia S, Cortes J, Huettner CS, Koschmieder S, Holyoake TL, Devine S, Caligiuri MA, Croce CM, Garzon R, Ogretmen B, Arlinghaus RB, Chen CS, Bittman R, Hokland P, Roy DC, Milojkovic D, Apperley J, Goldman JM, Reid A, Mulloy JC, Bhatia R, Marcucci G, Perrotti D. Neviani P, et al. Among authors: chen cs. J Clin Invest. 2013 Oct;123(10):4144-57. doi: 10.1172/JCI68951. Epub 2013 Sep 3. J Clin Invest. 2013. PMID: 23999433 Free PMC article.

10

Targeting endoplasmic reticulum stress and Akt with OSU-03012 and gefitinib or erlotinib to overcome resistance to epidermal growth factor receptor inhibitors.

Wang YC, Kulp SK, Wang D, Yang CC, Sargeant AM, Hung JH, Kashida Y, Yamaguchi M, Chang GD, Chen CS. Wang YC, et al. Among authors: chen cs. Cancer Res. 2008 Apr 15;68(8):2820-30. doi: 10.1158/0008-5472.CAN-07-1336. Cancer Res. 2008. PMID: 18413750 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

2,455 results

Search Page

Filters