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The majority of animal genes are required for wild-type fitness.
Ramani AK, Chuluunbaatar T, Verster AJ, Na H, Vu V, Pelte N, Wannissorn N, Jiao A, Fraser AG. Ramani AK, et al. Among authors: pelte n. Cell. 2012 Feb 17;148(4):792-802. doi: 10.1016/j.cell.2012.01.019. Cell. 2012. PMID: 22341449 Free article.
Cytokine Diedel and a viral homologue suppress the IMD pathway in Drosophila.
Lamiable O, Kellenberger C, Kemp C, Troxler L, Pelte N, Boutros M, Marques JT, Daeffler L, Hoffmann JA, Roussel A, Imler JL. Lamiable O, et al. Among authors: pelte n. Proc Natl Acad Sci U S A. 2016 Jan 19;113(3):698-703. doi: 10.1073/pnas.1516122113. Epub 2016 Jan 6. Proc Natl Acad Sci U S A. 2016. PMID: 26739560 Free PMC article.