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A new mutational AKTivation in the PI3K pathway.
Brugge J, Hung MC, Mills GB. Brugge J, et al. Among authors: mills gb. Cancer Cell. 2007 Aug;12(2):104-7. doi: 10.1016/j.ccr.2007.07.014. Cancer Cell. 2007. PMID: 17692802 Free article. Review.
A functional genetic approach identifies the PI3K pathway as a major determinant of trastuzumab resistance in breast cancer.
Berns K, Horlings HM, Hennessy BT, Madiredjo M, Hijmans EM, Beelen K, Linn SC, Gonzalez-Angulo AM, Stemke-Hale K, Hauptmann M, Beijersbergen RL, Mills GB, van de Vijver MJ, Bernards R. Berns K, et al. Among authors: mills gb. Cancer Cell. 2007 Oct;12(4):395-402. doi: 10.1016/j.ccr.2007.08.030. Cancer Cell. 2007. PMID: 17936563 Free article. Clinical Trial.
AKT-independent signaling downstream of oncogenic PIK3CA mutations in human cancer.
Vasudevan KM, Barbie DA, Davies MA, Rabinovsky R, McNear CJ, Kim JJ, Hennessy BT, Tseng H, Pochanard P, Kim SY, Dunn IF, Schinzel AC, Sandy P, Hoersch S, Sheng Q, Gupta PB, Boehm JS, Reiling JH, Silver S, Lu Y, Stemke-Hale K, Dutta B, Joy C, Sahin AA, Gonzalez-Angulo AM, Lluch A, Rameh LE, Jacks T, Root DE, Lander ES, Mills GB, Hahn WC, Sellers WR, Garraway LA. Vasudevan KM, et al. Among authors: mills gb. Cancer Cell. 2009 Jul 7;16(1):21-32. doi: 10.1016/j.ccr.2009.04.012. Cancer Cell. 2009. PMID: 19573809 Free PMC article.
Dose-dependent induction of distinct phenotypic responses to Notch pathway activation in mammary epithelial cells.
Mazzone M, Selfors LM, Albeck J, Overholtzer M, Sale S, Carroll DL, Pandya D, Lu Y, Mills GB, Aster JC, Artavanis-Tsakonas S, Brugge JS. Mazzone M, et al. Among authors: mills gb. Proc Natl Acad Sci U S A. 2010 Mar 16;107(11):5012-7. doi: 10.1073/pnas.1000896107. Epub 2010 Mar 1. Proc Natl Acad Sci U S A. 2010. PMID: 20194747 Free PMC article.
PTK6 regulates IGF-1-induced anchorage-independent survival.
Irie HY, Shrestha Y, Selfors LM, Frye F, Iida N, Wang Z, Zou L, Yao J, Lu Y, Epstein CB, Natesan S, Richardson AL, Polyak K, Mills GB, Hahn WC, Brugge JS. Irie HY, et al. Among authors: mills gb. PLoS One. 2010 Jul 23;5(7):e11729. doi: 10.1371/journal.pone.0011729. PLoS One. 2010. PMID: 20668531 Free PMC article.
Recombinant human erythropoietin antagonizes trastuzumab treatment of breast cancer cells via Jak2-mediated Src activation and PTEN inactivation.
Liang K, Esteva FJ, Albarracin C, Stemke-Hale K, Lu Y, Bianchini G, Yang CY, Li Y, Li X, Chen CT, Mills GB, Hortobagyi GN, Mendelsohn J, Hung MC, Fan Z. Liang K, et al. Among authors: mills gb. Cancer Cell. 2010 Nov 16;18(5):423-35. doi: 10.1016/j.ccr.2010.10.025. Cancer Cell. 2010. PMID: 21075308 Free PMC article.
1,152 results