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One small step for a yeast--microevolution within macrophages renders Candida glabrata hypervirulent due to a single point mutation.
Brunke S, Seider K, Fischer D, Jacobsen ID, Kasper L, Jablonowski N, Wartenberg A, Bader O, Enache-Angoulvant A, Schaller M, d'Enfert C, Hube B. Brunke S, et al. Among authors: schaller m. PLoS Pathog. 2014 Oct 30;10(10):e1004478. doi: 10.1371/journal.ppat.1004478. eCollection 2014 Oct. PLoS Pathog. 2014. PMID: 25356907 Free PMC article.
Candida albicans-Induced Epithelial Damage Mediates Translocation through Intestinal Barriers.
Allert S, Förster TM, Svensson CM, Richardson JP, Pawlik T, Hebecker B, Rudolphi S, Juraschitz M, Schaller M, Blagojevic M, Morschhäuser J, Figge MT, Jacobsen ID, Naglik JR, Kasper L, Mogavero S, Hube B. Allert S, et al. Among authors: schaller m. mBio. 2018 Jun 5;9(3):e00915-18. doi: 10.1128/mBio.00915-18. mBio. 2018. PMID: 29871918 Free PMC article.
882 results