Nikan M - Search Results

1

Small-molecule-induced DNA damage identifies alternative DNA structures in human genes.

Rodriguez R, Miller KM, Forment JV, Bradshaw CR, Nikan M, Britton S, Oelschlaegel T, Xhemalce B, Balasubramanian S, Jackson SP. Rodriguez R, et al. Among authors: nikan m. Nat Chem Biol. 2012 Feb 5;8(3):301-10. doi: 10.1038/nchembio.780. Nat Chem Biol. 2012. PMID: 22306580 Free PMC article.

2

A non-canonical DNA structure is a binding motif for the transcription factor SP1 in vitro.

Raiber EA, Kranaster R, Lam E, Nikan M, Balasubramanian S. Raiber EA, et al. Among authors: nikan m. Nucleic Acids Res. 2012 Feb;40(4):1499-508. doi: 10.1093/nar/gkr882. Epub 2011 Oct 22. Nucleic Acids Res. 2012. PMID: 22021377 Free PMC article.

3

An acetylene-bridged 6,8-purine dimer as a fluorescent switch-on probe for parallel G-quadruplexes.

Nikan M, Di Antonio M, Abecassis K, McLuckie K, Balasubramanian S. Nikan M, et al. Angew Chem Int Ed Engl. 2013 Jan 28;52(5):1428-31. doi: 10.1002/anie.201207075. Epub 2012 Dec 13. Angew Chem Int Ed Engl. 2013. PMID: 23238938 Free PMC article. No abstract available.

4

Crystal structure of a template-assembled synthetic G-quadruplex.

Nikan M, Patrick BO, Sherman JC. Nikan M, et al. Chembiochem. 2012 Jul 9;13(10):1413-5. doi: 10.1002/cbic.201200262. Epub 2012 May 24. Chembiochem. 2012. PMID: 22628361 No abstract available.

5

Template-assembled synthetic G-quartets (TASQs).

Nikan M, Sherman JC. Nikan M, et al. Angew Chem Int Ed Engl. 2008;47(26):4900-2. doi: 10.1002/anie.200704199. Angew Chem Int Ed Engl. 2008. PMID: 18496796 No abstract available.

6

Cation-complexation behavior of template-assembled synthetic G-quartets.

Nikan M, Sherman JC. Nikan M, et al. J Org Chem. 2009 Aug 7;74(15):5211-8. doi: 10.1021/jo9001245. J Org Chem. 2009. PMID: 19518105

7

Comparison of partially and fully chemically-modified siRNA in conjugate-mediated delivery in vivo.

Hassler MR, Turanov AA, Alterman JF, Haraszti RA, Coles AH, Osborn MF, Echeverria D, Nikan M, Salomon WE, Roux L, Godinho BMDC, Davis SM, Morrissey DV, Zamore PD, Karumanchi SA, Moore MJ, Aronin N, Khvorova A. Hassler MR, et al. Among authors: nikan m. Nucleic Acids Res. 2018 Mar 16;46(5):2185-2196. doi: 10.1093/nar/gky037. Nucleic Acids Res. 2018. PMID: 29432571 Free PMC article.

8

Guanabenz (Wytensin™) selectively enhances uptake and efficacy of hydrophobically modified siRNAs.

Osborn MF, Alterman JF, Nikan M, Cao H, Didiot MC, Hassler MR, Coles AH, Khvorova A. Osborn MF, et al. Among authors: nikan m. Nucleic Acids Res. 2015 Oct 15;43(18):8664-72. doi: 10.1093/nar/gkv942. Epub 2015 Sep 22. Nucleic Acids Res. 2015. PMID: 26400165 Free PMC article.

9

Glucagon Like Peptide 1 Receptor Agonists for Targeted Delivery of Antisense Oligonucleotides to Pancreatic Beta Cell.

Knerr L, Prakash TP, Lee R, Drury Iii WJ, Nikan M, Fu W, Pirie E, Maria L, Valeur E, Hayen A, Ölwegård-Halvarsson M, Broddefalk J, Ämmälä C, Østergaard ME, Meuller J, Sundström L, Andersson P, Janzén D, Jansson-Löfmark R, Seth PP, Andersson S. Knerr L, et al. Among authors: nikan m. J Am Chem Soc. 2021 Mar 10;143(9):3416-3429. doi: 10.1021/jacs.0c12043. Epub 2021 Feb 24. J Am Chem Soc. 2021. PMID: 33626278

10

Hydrophobicity drives the systemic distribution of lipid-conjugated siRNAs via lipid transport pathways.

Osborn MF, Coles AH, Biscans A, Haraszti RA, Roux L, Davis S, Ly S, Echeverria D, Hassler MR, Godinho BMDC, Nikan M, Khvorova A. Osborn MF, et al. Among authors: nikan m. Nucleic Acids Res. 2019 Feb 20;47(3):1070-1081. doi: 10.1093/nar/gky1232. Nucleic Acids Res. 2019. PMID: 30535404 Free PMC article.

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