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Liposomes loaded with paclitaxel and modified with novel triphenylphosphonium-PEG-PE conjugate possess low toxicity, target mitochondria and demonstrate enhanced antitumor effects in vitro and in vivo.
Biswas S, Dodwadkar NS, Deshpande PP, Torchilin VP. Biswas S, et al. Among authors: torchilin vp. J Control Release. 2012 May 10;159(3):393-402. doi: 10.1016/j.jconrel.2012.01.009. Epub 2012 Jan 20. J Control Release. 2012. PMID: 22286008 Free PMC article.
Hypoxia-sensitive drug delivery to tumors.
Filipczak N, Joshi U, Attia SA, Berger Fridman I, Cohen S, Konry T, Torchilin V. Filipczak N, et al. J Control Release. 2022 Jan;341:431-442. doi: 10.1016/j.jconrel.2021.11.034. Epub 2021 Nov 24. J Control Release. 2022. PMID: 34838607
520 results