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Wnt activity defines colon cancer stem cells and is regulated by the microenvironment.
Vermeulen L, De Sousa E Melo F, van der Heijden M, Cameron K, de Jong JH, Borovski T, Tuynman JB, Todaro M, Merz C, Rodermond H, Sprick MR, Kemper K, Richel DJ, Stassi G, Medema JP. Vermeulen L, et al. Among authors: de sousa e melo f, de jong jh. Nat Cell Biol. 2010 May;12(5):468-76. doi: 10.1038/ncb2048. Epub 2010 Apr 25. Nat Cell Biol. 2010. PMID: 20418870
Cancer stem cell niche: the place to be.
Borovski T, De Sousa E Melo F, Vermeulen L, Medema JP. Borovski T, et al. Among authors: de sousa e melo f. Cancer Res. 2011 Feb 1;71(3):634-9. doi: 10.1158/0008-5472.CAN-10-3220. Epub 2011 Jan 25. Cancer Res. 2011. PMID: 21266356 Free article. Review.
Methylation of cancer-stem-cell-associated Wnt target genes predicts poor prognosis in colorectal cancer patients.
de Sousa E Melo F, Colak S, Buikhuisen J, Koster J, Cameron K, de Jong JH, Tuynman JB, Prasetyanti PR, Fessler E, van den Bergh SP, Rodermond H, Dekker E, van der Loos CM, Pals ST, van de Vijver MJ, Versteeg R, Richel DJ, Vermeulen L, Medema JP. de Sousa E Melo F, et al. Among authors: de jong jh. Cell Stem Cell. 2011 Nov 4;9(5):476-85. doi: 10.1016/j.stem.2011.10.008. Cell Stem Cell. 2011. PMID: 22056143 Free article.
Cancer heterogeneity--a multifaceted view.
De Sousa E Melo F, Vermeulen L, Fessler E, Medema JP. De Sousa E Melo F, et al. EMBO Rep. 2013 Aug;14(8):686-95. doi: 10.1038/embor.2013.92. Epub 2013 Jul 12. EMBO Rep. 2013. PMID: 23846313 Free PMC article. Review.
Isolation and propagation of colon cancer stem cells.
Prasetyanti PR, Zimberlin C, De Sousa E Melo F, Medema JP. Prasetyanti PR, et al. Among authors: de sousa e melo f. Methods Mol Biol. 2013;1035:247-59. doi: 10.1007/978-1-62703-508-8_21. Methods Mol Biol. 2013. PMID: 23959997
Stem cell functionality is microenvironmentally defined during tumour expansion and therapy response in colon cancer.
Lenos KJ, Miedema DM, Lodestijn SC, Nijman LE, van den Bosch T, Romero Ros X, Lourenço FC, Lecca MC, van der Heijden M, van Neerven SM, van Oort A, Leveille N, Adam RS, de Sousa E Melo F, Otten J, Veerman P, Hypolite G, Koens L, Lyons SK, Stassi G, Winton DJ, Medema JP, Morrissey E, Bijlsma MF, Vermeulen L. Lenos KJ, et al. Among authors: de sousa e melo f. Nat Cell Biol. 2018 Oct;20(10):1193-1202. doi: 10.1038/s41556-018-0179-z. Epub 2018 Sep 3. Nat Cell Biol. 2018. PMID: 30177776 Free PMC article.
Axing Wnt signals.
De Sousa E Melo F, Medema JP. De Sousa E Melo F, et al. Cell Res. 2012 Jan;22(1):9-11. doi: 10.1038/cr.2011.141. Epub 2011 Aug 30. Cell Res. 2012. PMID: 21876559 Free PMC article. No abstract available.
41 results