Copeland WC - Search Results

1

RECQL4 localizes to mitochondria and preserves mitochondrial DNA integrity.

Croteau DL, Rossi ML, Canugovi C, Tian J, Sykora P, Ramamoorthy M, Wang ZM, Singh DK, Akbari M, Kasiviswanathan R, Copeland WC, Bohr VA. Croteau DL, et al. Among authors: copeland wc. Aging Cell. 2012 Jun;11(3):456-66. doi: 10.1111/j.1474-9726.2012.00803.x. Epub 2012 Mar 2. Aging Cell. 2012. PMID: 22296597 Free PMC article.

2

DNA base excision repair activities and pathway function in mitochondrial and cellular lysates from cells lacking mitochondrial DNA.

Stuart JA, Hashiguchi K, Wilson DM 3rd, Copeland WC, Souza-Pinto NC, Bohr VA. Stuart JA, et al. Among authors: copeland wc. Nucleic Acids Res. 2004 Apr 23;32(7):2181-92. doi: 10.1093/nar/gkh533. Print 2004. Nucleic Acids Res. 2004. PMID: 15107486 Free PMC article.

3

R964C mutation of DNA polymerase gamma imparts increased stavudine toxicity by decreasing nucleoside analog discrimination and impairing polymerase activity.

Bailey CM, Kasiviswanathan R, Copeland WC, Anderson KS. Bailey CM, et al. Among authors: copeland wc. Antimicrob Agents Chemother. 2009 Jun;53(6):2610-2. doi: 10.1128/AAC.01659-08. Epub 2009 Apr 13. Antimicrob Agents Chemother. 2009. PMID: 19364868 Free PMC article.

4

Disease mutations in the human mitochondrial DNA polymerase thumb subdomain impart severe defects in mitochondrial DNA replication.

Kasiviswanathan R, Longley MJ, Chan SS, Copeland WC. Kasiviswanathan R, et al. Among authors: copeland wc. J Biol Chem. 2009 Jul 17;284(29):19501-10. doi: 10.1074/jbc.M109.011940. Epub 2009 May 28. J Biol Chem. 2009. PMID: 19478085 Free PMC article.

5

Purification and functional characterization of human mitochondrial DNA polymerase gamma harboring disease mutations.

Kasiviswanathan R, Longley MJ, Young MJ, Copeland WC. Kasiviswanathan R, et al. Among authors: copeland wc. Methods. 2010 Aug;51(4):379-84. doi: 10.1016/j.ymeth.2010.02.015. Epub 2010 Feb 20. Methods. 2010. PMID: 20176107 Free PMC article. Review.

6

Biochemical analysis of human POLG2 variants associated with mitochondrial disease.

Young MJ, Longley MJ, Li FY, Kasiviswanathan R, Wong LJ, Copeland WC. Young MJ, et al. Among authors: copeland wc. Hum Mol Genet. 2011 Aug 1;20(15):3052-66. doi: 10.1093/hmg/ddr209. Epub 2011 May 9. Hum Mol Genet. 2011. PMID: 21555342 Free PMC article.

7

Ribonucleotide discrimination and reverse transcription by the human mitochondrial DNA polymerase.

Kasiviswanathan R, Copeland WC. Kasiviswanathan R, et al. Among authors: copeland wc. J Biol Chem. 2011 Sep 9;286(36):31490-500. doi: 10.1074/jbc.M111.252460. Epub 2011 Jul 21. J Biol Chem. 2011. PMID: 21778232 Free PMC article.

8

Biochemical analysis of the G517V POLG variant reveals wild-type like activity.

Kasiviswanathan R, Copeland WC. Kasiviswanathan R, et al. Among authors: copeland wc. Mitochondrion. 2011 Nov;11(6):929-34. doi: 10.1016/j.mito.2011.08.003. Epub 2011 Aug 11. Mitochondrion. 2011. PMID: 21856450 Free PMC article.

9

Mechanism of interaction of human mitochondrial DNA polymerase γ with the novel nucleoside reverse transcriptase inhibitor 4'-ethynyl-2-fluoro-2'-deoxyadenosine indicates a low potential for host toxicity.

Sohl CD, Singh K, Kasiviswanathan R, Copeland WC, Mitsuya H, Sarafianos SG, Anderson KS. Sohl CD, et al. Among authors: copeland wc. Antimicrob Agents Chemother. 2012 Mar;56(3):1630-4. doi: 10.1128/AAC.05729-11. Epub 2011 Dec 12. Antimicrob Agents Chemother. 2012. PMID: 22155823 Free PMC article.

10

Human mitochondrial DNA polymerase γ exhibits potential for bypass and mutagenesis at UV-induced cyclobutane thymine dimers.

Kasiviswanathan R, Gustafson MA, Copeland WC, Meyer JN. Kasiviswanathan R, et al. Among authors: copeland wc. J Biol Chem. 2012 Mar 16;287(12):9222-9. doi: 10.1074/jbc.M111.306852. Epub 2011 Dec 21. J Biol Chem. 2012. PMID: 22194617 Free PMC article.

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