O'Brien TJ - Search Results

1

Identification of new epilepsy treatments: issues in preclinical methodology.

Galanopoulou AS, Buckmaster PS, Staley KJ, Moshé SL, Perucca E, Engel J Jr, Löscher W, Noebels JL, Pitkänen A, Stables J, White HS, O'Brien TJ, Simonato M; American Epilepsy Society Basic Science Committee And The International League Against Epilepsy Working Group On Recommendations For Preclinical Epilepsy Drug Discovery. Galanopoulou AS, et al. Epilepsia. 2012 Mar;53(3):571-82. doi: 10.1111/j.1528-1167.2011.03391.x. Epub 2012 Jan 31. Epilepsia. 2012. PMID: 22292566 Free PMC article. Review.

2

Seizure control in antiepileptic drug-treated pregnancy.

Vajda FJ, Hitchcock A, Graham J, O'Brien T, Lander C, Eadie M. Vajda FJ, et al. Epilepsia. 2008 Jan;49(1):172-6. doi: 10.1111/j.1528-1167.2007.01412.x. Epub 2007 Nov 21. Epilepsia. 2008. PMID: 18031551 Free article.

3

Multidrug-resistant genotype (ABCB1) and seizure recurrence in newly treated epilepsy: data from international pharmacogenetic cohorts.

Szoeke C, Sills GJ, Kwan P, Petrovski S, Newton M, Hitiris N, Baum L, Berkovic SF, Brodie MJ, Sheffield LJ, O'Brien TJ. Szoeke C, et al. Epilepsia. 2009 Jul;50(7):1689-96. doi: 10.1111/j.1528-1167.2009.02059.x. Epub 2009 May 11. Epilepsia. 2009. PMID: 19453704 Free article.

4

Surgery for temporal lobe epilepsy associated with mesial temporal sclerosis in the older patient: a long-term follow-up.

Murphy M, Smith PD, Wood M, Bowden S, O'Brien TJ, Bulluss KJ, Cook MJ. Murphy M, et al. Epilepsia. 2010 Jun;51(6):1024-9. doi: 10.1111/j.1528-1167.2009.02430.x. Epub 2010 Feb 19. Epilepsia. 2010. PMID: 20196776 Free article.

5

Focal administration of neuropeptide Y into the S2 somatosensory cortex maximally suppresses absence seizures in a genetic rat model.

van Raay L, Jovanovska V, Morris MJ, O'Brien TJ. van Raay L, et al. Epilepsia. 2012 Mar;53(3):477-84. doi: 10.1111/j.1528-1167.2011.03370.x. Epub 2012 Jan 5. Epilepsia. 2012. PMID: 22220638 Free article.

6

Regulators of synaptic transmission: roles in the pathogenesis and treatment of epilepsy.

Casillas-Espinosa PM, Powell KL, O'Brien TJ. Casillas-Espinosa PM, et al. Epilepsia. 2012 Dec;53 Suppl 9:41-58. doi: 10.1111/epi.12034. Epilepsia. 2012. PMID: 23216578 Free article. Review.

7

Issues for new antiepilepsy drug development.

Simonato M, French JA, Galanopoulou AS, O'Brien TJ. Simonato M, et al. Curr Opin Neurol. 2013 Apr;26(2):195-200. doi: 10.1097/WCO.0b013e32835efe29. Curr Opin Neurol. 2013. PMID: 23406913 Free PMC article. Review.

8

Joint AES/ILAE translational workshop to optimize preclinical epilepsy research.

Galanopoulou AS, Simonato M, French JA, O'Brien TJ. Galanopoulou AS, et al. Epilepsia. 2013 Aug;54 Suppl 4:1-2. doi: 10.1111/epi.12293. Epilepsia. 2013. PMID: 23909848 Free article. No abstract available.

9

Brooks-Kayal AR, Bath KG, Berg AT, Galanopoulou AS, Holmes GL, Jensen FE, Kanner AM, O'Brien TJ, Whittemore VH, Winawer MR, Patel M, Scharfman HE. Brooks-Kayal AR, et al. Epilepsia. 2013 Aug;54 Suppl 4(0 4):44-60. doi: 10.1111/epi.12298. Epilepsia. 2013. PMID: 23909853 Free PMC article. Review.

10

Proposal for a "phase II" multicenter trial model for preclinical new antiepilepsy therapy development.

O'Brien TJ, Ben-Menachem E, Bertram EH 3rd, Collins SD, Kokaia M, Lerche H, Klitgaard H, Staley KJ, Vaudano E, Walker MC, Simonato M. O'Brien TJ, et al. Epilepsia. 2013 Aug;54 Suppl 4:70-4. doi: 10.1111/epi.12300. Epilepsia. 2013. PMID: 23909855 Free article. Review.

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