Löscher W - Search Results

1

Identification of new epilepsy treatments: issues in preclinical methodology.

Galanopoulou AS, Buckmaster PS, Staley KJ, Moshé SL, Perucca E, Engel J Jr, Löscher W, Noebels JL, Pitkänen A, Stables J, White HS, O'Brien TJ, Simonato M; American Epilepsy Society Basic Science Committee And The International League Against Epilepsy Working Group On Recommendations For Preclinical Epilepsy Drug Discovery. Galanopoulou AS, et al. Among authors: loscher w. Epilepsia. 2012 Mar;53(3):571-82. doi: 10.1111/j.1528-1167.2011.03391.x. Epub 2012 Jan 31. Epilepsia. 2012. PMID: 22292566 Free PMC article. Review.

2

Which animal models should be used in the search for new antiepileptic drugs? A proposal based on experimental and clinical considerations.

Löscher W, Schmidt D. Löscher W, et al. Epilepsy Res. 1988 May-Jun;2(3):145-81. doi: 10.1016/0920-1211(88)90054-x. Epilepsy Res. 1988. PMID: 3058469 Review. No abstract available.

3

Diazepam increases gamma-aminobutyric acid in human cerebrospinal fluid.

Löscher W, Schmidt D. Löscher W, et al. J Neurochem. 1987 Jul;49(1):152-7. doi: 10.1111/j.1471-4159.1987.tb03407.x. J Neurochem. 1987. PMID: 3585326

4

Evaluation of epileptic dogs as an animal model of human epilepsy.

Löscher W, Schwartz-Porsche D, Frey HH, Schmidt D. Löscher W, et al. Arzneimittelforschung. 1985;35(1):82-7. Arzneimittelforschung. 1985. PMID: 4039156

5

Monitoring of gamma-aminobutyric acid in human cerebrospinal fluid: downward revision of previous control values.

Löscher W, Schmidt D. Löscher W, et al. Ther Drug Monit. 1984;6(2):227-31. doi: 10.1097/00007691-198406000-00017. Ther Drug Monit. 1984. PMID: 6740742

6

Increase of human plasma GABA by sodium valproate.

Löscher W, Schmidt D. Löscher W, et al. Epilepsia. 1980 Dec;21(6):611-5. doi: 10.1111/j.1528-1157.1980.tb04314.x. Epilepsia. 1980. PMID: 6777153

7

Plasma GABA levels in neurological patients under treatment with valproic acid.

Löscher W, Schmidt D. Löscher W, et al. Life Sci. 1981 May 21;28(21):283-8. doi: 10.1016/0024-3205(81)90504-x. Life Sci. 1981. PMID: 6789023 No abstract available.

8

Plasma and cerebrospinal fluid gamma-aminobutyric acid in neurological disorders.

Schmidt D, Löscher W. Schmidt D, et al. Among authors: loscher w. J Neurol Neurosurg Psychiatry. 1982 Oct;45(10):931-5. doi: 10.1136/jnnp.45.10.931. J Neurol Neurosurg Psychiatry. 1982. PMID: 7143013 Free PMC article.

9

Stability of gamma-aminobutyric acid in human cerebrospinal fluid and plasma.

Löscher W, Schmidt D. Löscher W, et al. Ther Drug Monit. 1981;3(1):109. Ther Drug Monit. 1981. PMID: 7233486 No abstract available.

10

Strategies in antiepileptic drug development: is rational drug design superior to random screening and structural variation?

Löscher W, Schmidt D. Löscher W, et al. Epilepsy Res. 1994 Feb;17(2):95-134. doi: 10.1016/0920-1211(94)90012-4. Epilepsy Res. 1994. PMID: 8194514 Review. No abstract available.

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