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Fetal stromal-dependent paracrine and intracrine vascular endothelial growth factor-a/vascular endothelial growth factor receptor-1 signaling promotes proliferation and motility of human primary myeloma cells.
Vincent L, Jin DK, Karajannis MA, Shido K, Hooper AT, Rashbaum WK, Pytowski B, Wu Y, Hicklin DJ, Zhu Z, Bohlen P, Niesvizky R, Rafii S. Vincent L, et al. Among authors: rafii s. Cancer Res. 2005 Apr 15;65(8):3185-92. doi: 10.1158/0008-5472.CAN-04-3598. Cancer Res. 2005. PMID: 15833849
VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche.
Kaplan RN, Riba RD, Zacharoulis S, Bramley AH, Vincent L, Costa C, MacDonald DD, Jin DK, Shido K, Kerns SA, Zhu Z, Hicklin D, Wu Y, Port JL, Altorki N, Port ER, Ruggero D, Shmelkov SV, Jensen KK, Rafii S, Lyden D. Kaplan RN, et al. Among authors: rafii s. Nature. 2005 Dec 8;438(7069):820-7. doi: 10.1038/nature04186. Nature. 2005. PMID: 16341007 Free PMC article.
Preparing the "soil": the premetastatic niche.
Kaplan RN, Rafii S, Lyden D. Kaplan RN, et al. Among authors: rafii s. Cancer Res. 2006 Dec 1;66(23):11089-93. doi: 10.1158/0008-5472.CAN-06-2407. Cancer Res. 2006. PMID: 17145848 Free PMC article. Review.
Inflammation joins the "niche".
Peinado H, Rafii S, Lyden D. Peinado H, et al. Among authors: rafii s. Cancer Cell. 2008 Nov 4;14(5):347-9. doi: 10.1016/j.ccr.2008.10.012. Cancer Cell. 2008. PMID: 18977322 Free PMC article.
Engraftment and reconstitution of hematopoiesis is dependent on VEGFR2-mediated regeneration of sinusoidal endothelial cells.
Hooper AT, Butler JM, Nolan DJ, Kranz A, Iida K, Kobayashi M, Kopp HG, Shido K, Petit I, Yanger K, James D, Witte L, Zhu Z, Wu Y, Pytowski B, Rosenwaks Z, Mittal V, Sato TN, Rafii S. Hooper AT, et al. Among authors: rafii s. Cell Stem Cell. 2009 Mar 6;4(3):263-74. doi: 10.1016/j.stem.2009.01.006. Cell Stem Cell. 2009. PMID: 19265665 Free PMC article.
Angiomodulin is a specific marker of vasculature and regulates vascular endothelial growth factor-A-dependent neoangiogenesis.
Hooper AT, Shmelkov SV, Gupta S, Milde T, Bambino K, Gillen K, Goetz M, Chavala S, Baljevic M, Murphy AJ, Valenzuela DM, Gale NW, Thurston G, Yancopoulos GD, Vahdat L, Evans T, Rafii S. Hooper AT, et al. Among authors: rafii s. Circ Res. 2009 Jul 17;105(2):201-8. doi: 10.1161/CIRCRESAHA.109.196790. Epub 2009 Jun 18. Circ Res. 2009. PMID: 19542015 Free PMC article.
359 results