Gimenez LE - Search Results

1

Role of receptor-attached phosphates in binding of visual and non-visual arrestins to G protein-coupled receptors.

Gimenez LE, Kook S, Vishnivetskiy SA, Ahmed MR, Gurevich EV, Gurevich VV. Gimenez LE, et al. J Biol Chem. 2012 Mar 16;287(12):9028-40. doi: 10.1074/jbc.M111.311803. Epub 2012 Jan 24. J Biol Chem. 2012. PMID: 22275358 Free PMC article.

2

Crystal structure of arrestin-3 reveals the basis of the difference in receptor binding between two non-visual subtypes.

Zhan X, Gimenez LE, Gurevich VV, Spiller BW. Zhan X, et al. Among authors: gimenez le. J Mol Biol. 2011 Feb 25;406(3):467-78. doi: 10.1016/j.jmb.2010.12.034. Epub 2011 Jan 6. J Mol Biol. 2011. PMID: 21215759 Free PMC article.

3

Few residues within an extensive binding interface drive receptor interaction and determine the specificity of arrestin proteins.

Vishnivetskiy SA, Gimenez LE, Francis DJ, Hanson SM, Hubbell WL, Klug CS, Gurevich VV. Vishnivetskiy SA, et al. Among authors: gimenez le. J Biol Chem. 2011 Jul 8;286(27):24288-99. doi: 10.1074/jbc.M110.213835. Epub 2011 Apr 6. J Biol Chem. 2011. PMID: 21471193 Free PMC article.

4

Silent scaffolds: inhibition OF c-Jun N-terminal kinase 3 activity in cell by dominant-negative arrestin-3 mutant.

Breitman M, Kook S, Gimenez LE, Lizama BN, Palazzo MC, Gurevich EV, Gurevich VV. Breitman M, et al. Among authors: gimenez le. J Biol Chem. 2012 Jun 1;287(23):19653-64. doi: 10.1074/jbc.M112.358192. Epub 2012 Apr 20. J Biol Chem. 2012. PMID: 22523077 Free PMC article.

5

Manipulation of very few receptor discriminator residues greatly enhances receptor specificity of non-visual arrestins.

Gimenez LE, Vishnivetskiy SA, Baameur F, Gurevich VV. Gimenez LE, et al. J Biol Chem. 2012 Aug 24;287(35):29495-505. doi: 10.1074/jbc.M112.366674. Epub 2012 Jul 11. J Biol Chem. 2012. PMID: 22787152 Free PMC article.

6

Targeting individual GPCRs with redesigned nonvisual arrestins.

Gimenez LE, Vishnivetskiy SA, Gurevich VV. Gimenez LE, et al. Handb Exp Pharmacol. 2014;219:153-70. doi: 10.1007/978-3-642-41199-1_8. Handb Exp Pharmacol. 2014. PMID: 24292829 Free PMC article.

7

Arrestin-3 binds the MAP kinase JNK3α2 via multiple sites on both domains.

Zhan X, Perez A, Gimenez LE, Vishnivetskiy SA, Gurevich VV. Zhan X, et al. Among authors: gimenez le. Cell Signal. 2014 Apr;26(4):766-76. doi: 10.1016/j.cellsig.2014.01.001. Epub 2014 Jan 8. Cell Signal. 2014. PMID: 24412749 Free PMC article.

8

Mutations in arrestin-3 differentially affect binding to neuropeptide Y receptor subtypes.

Gimenez LE, Babilon S, Wanka L, Beck-Sickinger AG, Gurevich VV. Gimenez LE, et al. Cell Signal. 2014 Jul;26(7):1523-31. doi: 10.1016/j.cellsig.2014.03.019. Epub 2014 Mar 29. Cell Signal. 2014. PMID: 24686081 Free PMC article.

9

A G Protein-biased Designer G Protein-coupled Receptor Useful for Studying the Physiological Relevance of Gq/11-dependent Signaling Pathways.

Hu J, Stern M, Gimenez LE, Wanka L, Zhu L, Rossi M, Meister J, Inoue A, Beck-Sickinger AG, Gurevich VV, Wess J. Hu J, et al. Among authors: gimenez le. J Biol Chem. 2016 Apr 8;291(15):7809-20. doi: 10.1074/jbc.M115.702282. Epub 2016 Feb 5. J Biol Chem. 2016. PMID: 26851281 Free PMC article.

10

Ligand-induced internalization and recycling of the human neuropeptide Y2 receptor is regulated by its carboxyl-terminal tail.

Walther C, Nagel S, Gimenez LE, Mörl K, Gurevich VV, Beck-Sickinger AG. Walther C, et al. Among authors: gimenez le. J Biol Chem. 2010 Dec 31;285(53):41578-90. doi: 10.1074/jbc.M110.162156. Epub 2010 Oct 18. J Biol Chem. 2010. PMID: 20959467 Free PMC article.

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