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p90RSK targets the ERK5-CHIP ubiquitin E3 ligase activity in diabetic hearts and promotes cardiac apoptosis and dysfunction.
Le NT, Takei Y, Shishido T, Woo CH, Chang E, Heo KS, Lee H, Lu Y, Morrell C, Oikawa M, McClain C, Wang X, Tournier C, Molina CA, Taunton J, Yan C, Fujiwara K, Patterson C, Yang J, Abe J. Le NT, et al. Among authors: takei y. Circ Res. 2012 Feb 17;110(4):536-50. doi: 10.1161/CIRCRESAHA.111.254730. Epub 2012 Jan 19. Circ Res. 2012. PMID: 22267842 Free PMC article.
Phosphorylation of protein inhibitor of activated STAT1 (PIAS1) by MAPK-activated protein kinase-2 inhibits endothelial inflammation via increasing both PIAS1 transrepression and SUMO E3 ligase activity.
Heo KS, Chang E, Takei Y, Le NT, Woo CH, Sullivan MA, Morrell C, Fujiwara K, Abe J. Heo KS, et al. Among authors: takei y. Arterioscler Thromb Vasc Biol. 2013 Feb;33(2):321-9. doi: 10.1161/ATVBAHA.112.300619. Epub 2012 Nov 29. Arterioscler Thromb Vasc Biol. 2013. PMID: 23202365 Free PMC article.
A crucial role for p90RSK-mediated reduction of ERK5 transcriptional activity in endothelial dysfunction and atherosclerosis.
Le NT, Heo KS, Takei Y, Lee H, Woo CH, Chang E, McClain C, Hurley C, Wang X, Li F, Xu H, Morrell C, Sullivan MA, Cohen MS, Serafimova IM, Taunton J, Fujiwara K, Abe J. Le NT, et al. Among authors: takei y. Circulation. 2013 Jan 29;127(4):486-99. doi: 10.1161/CIRCULATIONAHA.112.116988. Epub 2012 Dec 14. Circulation. 2013. PMID: 23243209 Free PMC article.
Identification of activators of ERK5 transcriptional activity by high-throughput screening and the role of endothelial ERK5 in vasoprotective effects induced by statins and antimalarial agents.
Le NT, Takei Y, Izawa-Ishizawa Y, Heo KS, Lee H, Smrcka AV, Miller BL, Ko KA, Ture S, Morrell C, Fujiwara K, Akaike M, Abe J. Le NT, et al. Among authors: takei y. J Immunol. 2014 Oct 1;193(7):3803-15. doi: 10.4049/jimmunol.1400571. Epub 2014 Sep 3. J Immunol. 2014. PMID: 25187658 Free PMC article.
Declining Prevalence of Human Papillomavirus Co-Infections Among Young Japanese Women With Cervical Cancer and Its Precursors.
Yoshiizumi E, Onuki M, Kukimoto I, Takahashi F, Matsui T, Hamasaki K, Kanao H, Nio A, Yahata H, Goda M, Yokoyama T, Hisa T, Tasaki K, Tenjimbayashi Y, Saji H, Kudaka W, Takei Y, Shigeta S, Motohara T, Matsumiya H, Nakamura K, Yoshida H, Ishikawa M, Hamanishi J, Nakai H, Mori-Uchino M, Hirashima Y, Sekizawa A, Yoshikawa H, Yaegashi N, Matsumoto K; MINT Study Group. Yoshiizumi E, et al. Among authors: takei y. J Med Virol. 2024 Dec;96(12):e70096. doi: 10.1002/jmv.70096. J Med Virol. 2024. PMID: 39639793
1,596 results