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p90RSK targets the ERK5-CHIP ubiquitin E3 ligase activity in diabetic hearts and promotes cardiac apoptosis and dysfunction.
Le NT, Takei Y, Shishido T, Woo CH, Chang E, Heo KS, Lee H, Lu Y, Morrell C, Oikawa M, McClain C, Wang X, Tournier C, Molina CA, Taunton J, Yan C, Fujiwara K, Patterson C, Yang J, Abe J. Le NT, et al. Among authors: chang e. Circ Res. 2012 Feb 17;110(4):536-50. doi: 10.1161/CIRCRESAHA.111.254730. Epub 2012 Jan 19. Circ Res. 2012. PMID: 22267842 Free PMC article.
Novel role of C terminus of Hsc70-interacting protein (CHIP) ubiquitin ligase on inhibiting cardiac apoptosis and dysfunction via regulating ERK5-mediated degradation of inducible cAMP early repressor.
Woo CH, Le NT, Shishido T, Chang E, Lee H, Heo KS, Mickelsen DM, Lu Y, McClain C, Spangenberg T, Yan C, Molina CA, Yang J, Patterson C, Abe J. Woo CH, et al. Among authors: chang e. FASEB J. 2010 Dec;24(12):4917-28. doi: 10.1096/fj.10-162636. Epub 2010 Aug 19. FASEB J. 2010. PMID: 20724525 Free PMC article.
Phosphorylation of protein inhibitor of activated STAT1 (PIAS1) by MAPK-activated protein kinase-2 inhibits endothelial inflammation via increasing both PIAS1 transrepression and SUMO E3 ligase activity.
Heo KS, Chang E, Takei Y, Le NT, Woo CH, Sullivan MA, Morrell C, Fujiwara K, Abe J. Heo KS, et al. Among authors: chang e. Arterioscler Thromb Vasc Biol. 2013 Feb;33(2):321-9. doi: 10.1161/ATVBAHA.112.300619. Epub 2012 Nov 29. Arterioscler Thromb Vasc Biol. 2013. PMID: 23202365 Free PMC article.
A crucial role for p90RSK-mediated reduction of ERK5 transcriptional activity in endothelial dysfunction and atherosclerosis.
Le NT, Heo KS, Takei Y, Lee H, Woo CH, Chang E, McClain C, Hurley C, Wang X, Li F, Xu H, Morrell C, Sullivan MA, Cohen MS, Serafimova IM, Taunton J, Fujiwara K, Abe J. Le NT, et al. Among authors: chang e. Circulation. 2013 Jan 29;127(4):486-99. doi: 10.1161/CIRCULATIONAHA.112.116988. Epub 2012 Dec 14. Circulation. 2013. PMID: 23243209 Free PMC article.
Outcome of extra-nodal follicular lymphoma affected by choice of induction chemoimmunotherapy and maintenance rituximab - real-world retrospective study.
Ng LCK, Ong SY, Huang X, Ghosh A, Nagarajan C, Goh YT, Chen Y, Lim FLWI, Tan MSY, Lee XH, Tan JY, Grigoropoulos NF, Yang VS, Hoe JTM, Chiang J, Chang EWY, Poon EYL, Tan YH, Somasundaram N, Tao M, Lim ST, Chan JY. Ng LCK, et al. Among authors: chang ewy. Leuk Lymphoma. 2024 Dec 28:1-7. doi: 10.1080/10428194.2024.2446615. Online ahead of print. Leuk Lymphoma. 2024. PMID: 39731562
4,746 results