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Abrogation of SRC homology region 2 domain-containing phosphatase 1 in tumor-specific T cells improves efficacy of adoptive immunotherapy by enhancing the effector function and accumulation of short-lived effector T cells in vivo.
Stromnes IM, Fowler C, Casamina CC, Georgopolos CM, McAfee MS, Schmitt TM, Tan X, Kim TD, Choi I, Blattman JN, Greenberg PD. Stromnes IM, et al. Among authors: blattman jn. J Immunol. 2012 Aug 15;189(4):1812-25. doi: 10.4049/jimmunol.1200552. Epub 2012 Jul 13. J Immunol. 2012. PMID: 22798667 Free PMC article.
TCR contact residue hydrophobicity is a hallmark of immunogenic CD8+ T cell epitopes.
Chowell D, Krishna S, Becker PD, Cocita C, Shu J, Tan X, Greenberg PD, Klavinskis LS, Blattman JN, Anderson KS. Chowell D, et al. Among authors: blattman jn. Proc Natl Acad Sci U S A. 2015 Apr 7;112(14):E1754-62. doi: 10.1073/pnas.1500973112. Epub 2015 Mar 23. Proc Natl Acad Sci U S A. 2015. PMID: 25831525 Free PMC article.
51 results