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Intracellular protein degradation in mammalian cells: recent developments.
Knecht E, Aguado C, Cárcel J, Esteban I, Esteve JM, Ghislat G, Moruno JF, Vidal JM, Sáez R. Knecht E, et al. Cell Mol Life Sci. 2009 Aug;66(15):2427-43. doi: 10.1007/s00018-009-0030-6. Epub 2009 Apr 28. Cell Mol Life Sci. 2009. PMID: 19399586 Free PMC article. Review.
Laforin, the most common protein mutated in Lafora disease, regulates autophagy.
Aguado C, Sarkar S, Korolchuk VI, Criado O, Vernia S, Boya P, Sanz P, de Córdoba SR, Knecht E, Rubinsztein DC. Aguado C, et al. Among authors: knecht e. Hum Mol Genet. 2010 Jul 15;19(14):2867-76. doi: 10.1093/hmg/ddq190. Epub 2010 May 7. Hum Mol Genet. 2010. PMID: 20453062 Free PMC article.
Malin knockout mice support a primary role of autophagy in the pathogenesis of Lafora disease.
Knecht E, Criado-García O, Aguado C, Gayarre J, Duran-Trio L, Garcia-Cabrero AM, Vernia S, San Millán B, Heredia M, Romá-Mateo C, Mouron S, Juana-López L, Domínguez M, Navarro C, Serratosa JM, Sanchez M, Sanz P, Bovolenta P, Rodríguez de Córdoba S. Knecht E, et al. Autophagy. 2012 Apr;8(4):701-3. doi: 10.4161/auto.19522. Epub 2012 Apr 1. Autophagy. 2012. PMID: 22361617 Free article. Review.
159 results