Stevens MF - Search Results

1

Quinol derivatives as potential trypanocidal agents.

Capes A, Patterson S, Wyllie S, Hallyburton I, Collie IT, McCarroll AJ, Stevens MF, Frearson JA, Wyatt PG, Fairlamb AH, Gilbert IH. Capes A, et al. Among authors: stevens mf. Bioorg Med Chem. 2012 Feb 15;20(4):1607-15. doi: 10.1016/j.bmc.2011.12.018. Epub 2011 Dec 27. Bioorg Med Chem. 2012. PMID: 22264753 Free PMC article.

2

Antitumor quinol PMX464 is a cytocidal anti-trypanosomal inhibitor targeting trypanothione metabolism.

König J, Wyllie S, Wells G, Stevens MF, Wyatt PG, Fairlamb AH. König J, et al. Among authors: stevens mf. J Biol Chem. 2011 Mar 11;286(10):8523-8533. doi: 10.1074/jbc.M110.214833. Epub 2011 Jan 6. J Biol Chem. 2011. PMID: 21212280 Free PMC article.

3

Quinols as novel therapeutic agents. 7.1 Synthesis of antitumor 4-[1-(arylsulfonyl-1H-indol-2-yl)]-4-hydroxycyclohexa-2,5-dien-1-ones by Sonogashira reactions.

McCarroll AJ, Bradshaw TD, Westwell AD, Matthews CS, Stevens MF. McCarroll AJ, et al. Among authors: stevens mf. J Med Chem. 2007 Apr 5;50(7):1707-10. doi: 10.1021/jm061163m. Epub 2007 Mar 8. J Med Chem. 2007. PMID: 17343370

4

Antitumor polycyclic acridines. 20. Search for DNA quadruplex binding selectivity in a series of 8,13-dimethylquino[4,3,2-kl]acridinium salts: telomere-targeted agents.

Cheng MK, Modi C, Cookson JC, Hutchinson I, Heald RA, McCarroll AJ, Missailidis S, Tanious F, Wilson WD, Mergny JL, Laughton CA, Stevens MF. Cheng MK, et al. Among authors: stevens mf. J Med Chem. 2008 Feb 28;51(4):963-75. doi: 10.1021/jm070587t. Epub 2008 Feb 2. J Med Chem. 2008. PMID: 18247546

5

Synthesis and properties of bioactive 2- and 3-amino-8-methyl-8H-quino[4,3,2-kl]acridine and 8,13-dimethyl-8H-quino[4,3,2-kl]acridinium salts.

Hutchinson I, McCarroll AJ, Heald RA, Stevens MF. Hutchinson I, et al. Among authors: stevens mf. Org Biomol Chem. 2004 Jan 21;2(2):220-8. doi: 10.1039/b310796p. Epub 2003 Dec 10. Org Biomol Chem. 2004. PMID: 14737646

6

Antitumor quinols: role of glutathione in modulating quinol-induced apoptosis and identification of putative cellular protein targets.

Chew EH, Matthews CS, Zhang J, McCarroll AJ, Hagen T, Stevens MF, Westwell AD, Bradshaw TD. Chew EH, et al. Among authors: stevens mf. Biochem Biophys Res Commun. 2006 Jul 21;346(1):242-51. doi: 10.1016/j.bbrc.2006.05.106. Epub 2006 May 26. Biochem Biophys Res Commun. 2006. PMID: 16756956

7

Synthesis of antitumour (1H-1,2,3-triazol-4-yl)-4-hydroxycyclohexa-2,5-dien-1-ones by copper-catalysed Huisgen cycloadditions.

McCarroll AJ, Matthews CS, Wells G, Bradshaw TD, Stevens MF. McCarroll AJ, et al. Among authors: stevens mf. Org Biomol Chem. 2010 May 7;8(9):2078-84. doi: 10.1039/b920039h. Epub 2010 Mar 3. Org Biomol Chem. 2010. PMID: 20401384

8

Antitumour benzothiazoles. Part 10: the synthesis and antitumour activity of benzothiazole substituted quinol derivatives.

Wells G, Bradshaw TD, Diana P, Seaton A, Shi DF, Westwell AD, Stevens MF. Wells G, et al. Among authors: stevens mf. Bioorg Med Chem Lett. 2000 Mar 6;10(5):513-5. doi: 10.1016/s0960-894x(00)00027-5. Bioorg Med Chem Lett. 2000. PMID: 10743960

9

Antitumour properties of fluorinated benzothiazole-substituted hydroxycyclohexa-2,5-dienones ('quinols').

Lion CJ, Matthews CS, Wells G, Bradshaw TD, Stevens MF, Westwell AD. Lion CJ, et al. Among authors: stevens mf. Bioorg Med Chem Lett. 2006 Oct 1;16(19):5005-8. doi: 10.1016/j.bmcl.2006.07.072. Bioorg Med Chem Lett. 2006. PMID: 16908135

10

Quinols as novel therapeutic agents. 2.(1) 4-(1-Arylsulfonylindol-2-yl)-4-hydroxycyclohexa-2,5-dien-1-ones and related agents as potent and selective antitumor agents.

Berry JM, Bradshaw TD, Fichtner I, Ren R, Schwalbe CH, Wells G, Chew EH, Stevens MF, Westwell AD. Berry JM, et al. Among authors: stevens mf. J Med Chem. 2005 Jan 27;48(2):639-44. doi: 10.1021/jm040859h. J Med Chem. 2005. PMID: 15658878

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